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TASTY trial: protocol for a study on the triad of nutrition, intestinal microbi...

Charneca, S; Hernando, A; Almada-Correia, I; Polido-Pereira, J; Vieira, A; Sousa, J; Almeida, AS; Motta, C; Barreto, G; Eklund, KK; Alonso-Pérez, A

Background The gut microbiota has been implicated in the onset and progression of Rheumatoid Arthritis (RA). It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. This disruption allows bacterial translocation, contributing to the perpetuation of the inflammatory process. Since diet is recognised as a key environmental factor influencing ...


A low fermentable oligo-di-mono saccharides and polyols (FODMAP) diet reduced p...

Marum, AP; Moreira, C; Saraiva, F; Tomas-Carus, P; Guerreiro, CS

Fibromyalgia (FM) is a chronic, rheumatic disease characterized by widespread myofascial pain, of unknown aetiology, having a major impact on quality of life (QOL). Available pharmacotherapy for FM is marginally effective. FM is associated with co-morbidities of gastrointestinal (GI) disorders and Irritable Bowel Syndrome (IBS). There is growing evidence that diets low in FODMAPs, “fermentable oligo-, di- or mo...


Diet therapy with FODMAPS restriction has benefits in Fibromyalgia?

Marun, AP; Moreira, C; Tomas-Carus, P; Saraiva, F; Guerreiro, CS

Rationale: The effects of a diet restriction in FODMAPs (Fermentable oligo-di-monosaccharides polyols) is being studied on the symptoms of Fibromyalgia (FM) and its impact on quality of life (QOL) besides the effect on gastrointestinal (GI) symptoms. High prevalence of functional GI disorders is found in FM and Low FODMAP Diet has growing scientific evidence as IBS (Irritable Bowel Syndrome) therapy. Methods: I...


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