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Body composition analysis in metastatic non-small-cell lung cancer: depicting s...

Mendes, José Leão; Ferreira, Rita Quaresma; Mata, Inês; Barreira, João Vasco; Rodrigues, Ysel Chiara; Dias, David Silva; Capelas, Manuel; Mäkitie, Antti

Background/Objectives: Sarcopenia is an emergent prognostic biomarker in clinical oncology. Albeit increasingly defined through skeletal muscle index (SMI) thresholding, literature cut-offs fail to discern heterogeneous baseline muscularity across populations. This study assesses the prognostic impact of using cohort-specific SMI thresholds in a Portuguese metastatic non-small-cell lung cancer (mNSCLC) cohort. ...


Body Composition Analysis in Metastatic Non-Small-Cell Lung Cancer: Depicting S...

Leão Mendes, José; Ferreira, Rita Quaresma; Mata, Inês; Vasco Barreira, João; Rodrigues, Ysel Chiara; Silva Dias, David; Capelas, Manuel Luís

Sarcopenia is an emergent prognostic biomarker in clinical oncology. Albeit increasingly defined through skeletal muscle index (SMI) thresholding, the literature cut-offs fail to discern heterogeneous baseline muscularity across populations. This study assesses the prognostic impact of using cohort-specific SMI thresholds in a Portuguese metastatic non-small-cell lung cancer (mNSCLC) cohort. : Retrospective stu...


BEST of ASCO Portugal 2024 - IG: BEST of ASCO Portugal 2024

Guerreiro, Inês

The treatment of lung cancer has evolved significantly in recent years, mainly due to the development of immunotherapy and molecular-targeted therapies. As with advanced disease, important advances have also been made in localized disease, which have resulted in changes in the treatment paradigm in this disease context. This article analyzes the main studies presented at the 2024 annual congress of the American...


Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms of the Rectum: A Case Report.

Verdasca, Filipa Ribeiro; Ferreira, Rita; Montenegro, Alexandra; Mendes, José Leão; Furtado, Ivánia; Escaleira, Rui; Fernandes, Válter; Seladas, Marta

Introduction: Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) represent roughly 1-2% of all colorectal malignancies. Given the rareness and heterogeneity of these mixed tumors, recognition and accurate diagnosis remain a challenge. In the absence of established guidelines, they are treated according to the standard of care for pure neuroendocrine carcinomas or adenocarcinomas from similar sites of ori...


A Fisioterapia no edema pós-cirúrgico do pé: revisão de literatura

Diogo, Andreia; Santos, Camila; Guerreiro, Inês; Appleton, Mafalda; Araújo, Margarida; Florindo, Margarida Maria Esteves

A formação do edema no pé após cirurgia pode ser a principal razão para a instalação da dor, disfunções da marcha e de prolongamento do período de recuperação. Esta revisão foi realizada com o objetivo de identificar os resultados da Fisioterapia no edema pós-cirúrgico do pé e de nomear componentes de avaliação importantes na escolha do programa de intervenção. A pesquisa foi realizada nas bases de dados, PubMe...


Evaluation of the seaweeds Chondrus crispus and Ulva lactuca as functional ingr...

Guerreiro, Inês; Magalhães, Rui; Coutinho, Filipe; Couto, Ana; Sousa, Sara; Delerue-Matos, Cristina; Domingues, Valentina F.; Oliva-Teles, Aires

The effect of a dietary incorporation of the seaweedsUlva lactucaandChondrus crispusas functional ingredients was evaluatedin gilthead seabream (Sparus aurata) juvenile growth, feed efficiency, muscle lipid composition, intermediary metabolism,oxidative status and gut histomorphology. Fish (15 g initial body weight) were fed with isoproteic (46%) and isolipidic (18%)diets with fish meal (FM) and plant feedstuff...


Effect of short chain fructooligosaccharides (scFOS) on immunological status an...

Guerreiro, Inês; Serra, Cláudia R.; Enes, Paula; Couto, Ana; Salvador, A. F.; Costas, Benjamín; Teles, Aires Oliva

The effects of dietary short chain fructooligosaccharides (scFOS) incorporation on hematology, fish immune status, gut microbiota composition, digestive enzymes activities, and gut morphology, was evaluated in gilthead sea bream (Sparus aurata) juveniles reared at 18 °C and 25 °C. For that purpose, fish with 32 g were fed diets including 0, 0.1, 0.25 and 0.5% scFOS during 8 weeks. Overall, scFOS had only minor ...


A minha escola fará diferença? influência da qualidade do contexto educativo no...

Guerreiro, Inês; Domingos, M. Alice; Almeida, Rita; Casimiro, Rute; Fuertes, Marina; Rosa, João

A investigação indica que a frequência de creche e JI podem promover o desenvolvimento infantil (revisão em Bairrão, 1998). Contudo, a educação de infância só terá consequências positivas se fornecermos um serviço educativo de qualidade (Formosinho, 1996; Oliveira-Formosinho, 2004, 2008, revisão em Fuertes, 2010).


Prevalência e etiologia dos retratamentos endodônticos na Clínica Dentária Egas...

Guerreiro, Inês; Proença, Luís; Mendes, José João; Azul, Ana Cristina


Impact of dietary protein hydrolysates on skeleton quality and proteome in Dipl...

Vareilles, Mahaut; Richard, Nadège; Gavaia, Paulo J.; Silva, Tomé S.; Cordeiro, O.; Guerreiro, Inês; Yúfera, M.; Batista, I.; Pires, C.

In order to investigate the effects of dietary protein hydrolysates (PH) on larval growth performance, skeleton quality and proteome expression, triplicate groups of white seabream (Diplodus sargus) larvae were co-fed from first-feeding with live feed and three microencapsulated diets differing in the molecular weight of their PH fraction (Control – inclusion of CPSP-90; H – inclusion of a high amount in 0.5–30...


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