Background/Objectives: Sarcopenia is an emergent prognostic biomarker in clinical oncology. Albeit increasingly defined through skeletal muscle index (SMI) thresholding, literature cut-offs fail to discern heterogeneous baseline muscularity across populations. This study assesses the prognostic impact of using cohort-specific SMI thresholds in a Portuguese metastatic non-small-cell lung cancer (mNSCLC) cohort. ...
Sarcopenia is an emergent prognostic biomarker in clinical oncology. Albeit increasingly defined through skeletal muscle index (SMI) thresholding, the literature cut-offs fail to discern heterogeneous baseline muscularity across populations. This study assesses the prognostic impact of using cohort-specific SMI thresholds in a Portuguese metastatic non-small-cell lung cancer (mNSCLC) cohort. : Retrospective stu...
The treatment of lung cancer has evolved significantly in recent years, mainly due to the development of immunotherapy and molecular-targeted therapies. As with advanced disease, important advances have also been made in localized disease, which have resulted in changes in the treatment paradigm in this disease context. This article analyzes the main studies presented at the 2024 annual congress of the American...
Introduction: Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) represent roughly 1-2% of all colorectal malignancies. Given the rareness and heterogeneity of these mixed tumors, recognition and accurate diagnosis remain a challenge. In the absence of established guidelines, they are treated according to the standard of care for pure neuroendocrine carcinomas or adenocarcinomas from similar sites of ori...
A formação do edema no pé após cirurgia pode ser a principal razão para a instalação da dor, disfunções da marcha e de prolongamento do período de recuperação. Esta revisão foi realizada com o objetivo de identificar os resultados da Fisioterapia no edema pós-cirúrgico do pé e de nomear componentes de avaliação importantes na escolha do programa de intervenção. A pesquisa foi realizada nas bases de dados, PubMe...
The effect of a dietary incorporation of the seaweedsUlva lactucaandChondrus crispusas functional ingredients was evaluatedin gilthead seabream (Sparus aurata) juvenile growth, feed efficiency, muscle lipid composition, intermediary metabolism,oxidative status and gut histomorphology. Fish (15 g initial body weight) were fed with isoproteic (46%) and isolipidic (18%)diets with fish meal (FM) and plant feedstuff...
The effects of dietary short chain fructooligosaccharides (scFOS) incorporation on hematology, fish immune status, gut microbiota composition, digestive enzymes activities, and gut morphology, was evaluated in gilthead sea bream (Sparus aurata) juveniles reared at 18 °C and 25 °C. For that purpose, fish with 32 g were fed diets including 0, 0.1, 0.25 and 0.5% scFOS during 8 weeks. Overall, scFOS had only minor ...
A investigação indica que a frequência de creche e JI podem promover o desenvolvimento infantil (revisão em Bairrão, 1998). Contudo, a educação de infância só terá consequências positivas se fornecermos um serviço educativo de qualidade (Formosinho, 1996; Oliveira-Formosinho, 2004, 2008, revisão em Fuertes, 2010).
In order to investigate the effects of dietary protein hydrolysates (PH) on larval growth performance, skeleton quality and proteome expression, triplicate groups of white seabream (Diplodus sargus) larvae were co-fed from first-feeding with live feed and three microencapsulated diets differing in the molecular weight of their PH fraction (Control – inclusion of CPSP-90; H – inclusion of a high amount in 0.5–30...