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Recommendations from a Portuguese Expert Group for Discontinuation of Tyrosine ...

Almeida, Antonio; Pierdomenico, Francesca; Guerrero, Blanca Polo; Saraiva, Filipa; Montalvão, Ana; Coutinho, Jorge; Mariz, Mário; Melo, Teresa

Until recently, the main goal of chronic myeloid leukemia therapy was disease control with the best overall survival, which required lifelong treatment. However, currently, the treatment-free remission concept is becoming an important goal in clinical practice, and several tyrosine kinase inhibitors discontinuation studies have shown that  round 50% of patients with a durable deep molecular response beyond majo...

Date: 2019   |   Origin: Acta Médica Portuguesa
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