2 documents found, page 1 of 1
The role of dorsomedial hypotalamus ionotropic glutamate receptors in the hyper...
Silva, Fernanda Cacilda dos Santos; Guidine, Patrícia Alves Maia; Machado, Natália Lima Santos; Xavier, Carlos Henrique; Menezes, Rodrigo Cunha Alvim deThe scorpion envenoming syndrome is an important worldwide public health problem due to its high incidence and potential severity of symptoms. Some studies address the high sensitivity of the central nervous system to this toxin action. It is known that cardiorespiratory manifestations involve the activation of the autonomic nervous system. However, the origin of this modulation remains unclear. Considering the...
Dose-dependent effect of carbamazepine on weanling rats submitted to subcutaneo...
Guidine, Patrícia Alves Maia; Assumpção, Gioconda; Santos, Tasso Moraes; Massensini, André Ricardo; Chianca Júnior, Deoclécio AlvesThe scorpion envenoming syndrome is a serious public health matter in Brazil. The most severe cases occur during childhood and elderly. Previous results from our laboratory suggest that the effects of scorpion toxins on the central nervous system play a major role on the lethality induced by scorpion envenoming. The aim of this work is to evaluate the therapeutic potential of carbamazepine (CBZ) injected i.p. 9...