7 documents found, page 1 of 1
Antiangiogenic and antioxidant in vitro properties of hydroethanolic extract fr...
Costa, Raquel; Azevedo, Daniela; Barata, Pedro; Soares, Raquel; Guido, Luís F.; Carvalho, Daniel O.The Euterpe oleracea fruit (açaí) is a promising source of polyphenols with health-promoting properties. To our knowledge, few studies have focused on the influence of açaí phytochemicals on angiogenesis, with a significant impact on cancer. This study aimed at investigating the phytochemical profile of a purple açaí hydroethanolic extract (AHE) obtained from a commercial dietary powder supplement by high-perfo...
Brewer’s spent grains protects against oxidative DNA damage in Saccharomyces ce...
Moreira, Manuela M.; Carvalho, Daniel O.; Oliveira, Rui Pedro Soares de; Johansson, Björn; Guido, Luís F.Brewer’s spent grain (BSG), obtained from barley malt during brewing, contains high amounts of phenolic acids, predominantly ferulic and p-coumaric acids. The protective effects of BSG extracts against oxidative DNA damage induced by H2O2 in Saccharomyces cerevisiae cells were investigated using an optimized yeast comet assay and flow cytometry. The results indicated that BSG extracts from black malt exhibited ...
Dose-dependent protective and inductive effects of xanthohumol on oxidative DNA...
Carvalho, Daniel O.; Oliveira, Rui Pedro Soares de; Johansson, Björn; Guido, Luís F.The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth in the presence of 5 mg/L of xanthohumol than cultures with only H2O2. Likewise, DNA damage assessed by the comet assay was significantly lower in cells co-inc...
Monomeric and oligomeric flavan-3-ols and antioxidant activity of leaves from d...
Ferreira da Vinha, Ana; Guido, Luís F.; Costa, Anabela S.G.; Alves, Rita C.; Oliveira, M. Beatriz P. P.The phenolic profile and antioxidant activity of three endemic Laurus sp. from Portugal were analysed. Dried leaves of L. nobilis L., L. azorica (Seub.) Franco, and L. novocanariensis Rivas Mart., Lousã, Fern. Prieto, E. Días, J. C. Costa & C. Aguiar, collected in the mainland and in the Azores and Madeira archipelagos, respectively, were used to prepare different extracts (aqueous, ethanolic and hydroalcoholic...
Monomeric and oligomeric flavan-3-ols and antioxidant activity of leaves from d...
Vinha, Ana F.; Guido, Luís F.; Costa, Anabela S. G.; Alves, Rita C.; Oliveira, M. Beatriz P. P.The phenolic profile and antioxidant activity of three endemic Laurus sp. from Portugal were analysed. Dried leaves of L. nobilis L., L. azorica (Seub.) Franco, and L. novocanariensis Rivas Mart., Lousã, Fern. Prieto, E. Días, J. C. Costa & C. Aguiar, collected in the mainland and in the Azores and Madeira archipelagos, respectively, were used to prepare different extracts (aqueous, ethanolic and hydroalcoholic...
Brewer's spent grain from different types of malt: Evaluation of the antioxidan...
Moreira, Manuela M.; Morais, Simone; Carvalho, Daniel O.; Barros, Aquiles A.; Delerue-Matos, Cristina; Guido, Luís F.The antioxidant activity and phenolic composition of brewer's spent grain (BSG) extracts obtained by microwave-assisted extraction from twomalt types (light and darkmalts) were investigated. The total phenolic content (TPC) and antioxidant activity among the light BSG extracts (pilsen, melano, melano 80 and carared)were significantly different (p b 0.05) compared to dark extracts (chocolate and black types), wi...
A novel application of microwave-assisted extraction of polyphenols from brewer...
Moreira, Manuela M.; Morais, Simone; Barros, Aquiles A.; Delerue-Matos, Cristina; Guido, Luís F.This paper reports a novel application of microwave-assisted extraction (MAE) of polyphenols from brewer’s spent grains (BSG). A 24 orthogonal composite design was used to obtain the optimal conditions of MAE. The influence of the MAE operational parameters (extraction time, temperature, solvent volume and stirring speed) on the extraction yield of ferulic acid was investigated through response surface methodol...