7 documents found, page 1 of 1
New Isoquinoline Alkaloids from Paraphaeosphaeria sporulosa F03, a Fungal Endop...
Amorim, Marcelo R. de [UNESP]; Paz, Tiago A. [UNESP]; Pinto, Luciano da S.; Hilario, Felipe [UNESP]; Zanini, Camila L.; Aguiar, Anna Caroline C.Made available in DSpace on 2022-04-28T17:30:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-19; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); As part of our continuing efforts to discover new bioactive compounds from endophytic fungal sources, we have investigated the extract of the Paraphaeosphaeria sporulosa F0...
The methionine 549 and leucine 552 residues of friedelin synthase from maytenus...
Mazzeu, Bruna F. [UNESP]; Souza-Moreira, Tatiana M. [UNESP]; Oliveira, Andrew A.; Remlinger, Melissa [UNESP]; Felippe, Lidiane G. [UNESP]Made available in DSpace on 2022-04-29T08:46:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-02; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Friedelin, a pentacyclic triterpene found in the leaves of the Celastraceae species, demon-strates numerous biological activities and is a precursor of quinonemethide trite...
Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV...
Freire, Marjorie C. L. C.; Noske, Gabriela D.; Bitencourt, Natália V. [UNESP]; Sanches, Paulo R. S. [UNESP]; Santos-Filho, Norival A. [UNESP]Made available in DSpace on 2022-04-29T08:32:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-02; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and public health sy...
In vitro bioassay guided anti-dermatophyte and cytotoxic activities from Piper ...
Freitas, Jolindo A. [UNESP]; Sorrechia, Rodrigo [UNESP]; Politi, Flávio A. S. [UNESP]; Santos, André G. [UNESP]; Rodrigues, Edvânio R. [UNESP]Made available in DSpace on 2021-06-25T10:33:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Dermatophytosis is a dermic disease caused by fungi. The aim of this study was to search anti-dermatophyte bioactive compounds in Piper umbellatum leaves. Cytotoxicity evaluation was performed against MRC-5 and HepG2 as a selectivity parameter. Crude ethanol extract presented MIC value of 39.1 μg/mL aga...
Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Rol...
Souza-Moreira, Tatiana M. [UNESP]; Alves, Thaís B. [UNESP]; Pinheiro, Karina A. [UNESP]; Felippe, Lidiane G. [UNESP]; De Lima, Gustavo M. A.Made available in DSpace on 2018-12-11T17:23:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-22; Among the biologically active triterpenes, friedelin has the most-rearranged structure produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In this study, we cloned and functionally characterized friedelin synthase and one cycloartenol synthase from Maytenus ilicifolia ...
Classical and hologram QSAR studies on a series of inhibitors of trypanosomatid...
Guido, Rafael V. C.; Castilho, Marcelo Santos; Mota, Sabrina G. R.; Oliva, Glaucius; Andricopulo, Adriano D.; Guido, Rafael V. C.Texto completo: acesso restrito. p. 768-781; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-12-05T15:11:05Z No. of bitstreams: 1 10.1002qsar.200710139.pdf: 343846 bytes, checksum: d0ad2b669216428580985a3321346ce3 (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-01-21T20:58:20Z (GMT) No. of bitstreams: 1 10.1002qsar.200710139.pdf: 343846 bytes, checksum: d0ad2b6692...
2D Quantitative structure–activity relationship studies on a series of choleste...
Castilho, Marcelo Santos; Guido, Rafael V. C.; Andricopulo, Adriano D.; Castilho, Marcelo Santos; Guido, Rafael V. C.; Andricopulo, Adriano D.Texto completo: acesso restrito. p. 6242-6252; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-14T17:06:46Z No. of bitstreams: 1 1-s2.0-S0968089607005445-main.pdf: 463973 bytes, checksum: a753790176d7a99f075fe5669cc452c4 (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-01-21T20:58:37Z (GMT) No. of bitstreams: 1 1-s2.0-S0968089607005445-main.pdf: 463973 bytes, ch...