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Development of a novel electrochemical biosensor based on plastic antibodies fo...

Carvalho, Margarida; Rocha, Sandra Moreira; Barroca-Ferreira, Jorge; Maia, Claudio J.; Guillade, Lucía; Correa-Duarte, Miguel A.; Passarinha, Luís A.

STEAP1 is a cell surface protein of the STEAP family whose main function focuses on intercellular communication and cell growth. STEAP1 is considered a promising putative biomarker and a candidate target for prostate cancer treatment. For specific and selective detection of STEAP1, a molecularly imprinted polymers (MIP) was developed on a screen-printed electrode (C-SPE) whose surface was modified with a nanoco...


Development of a novel electrochemical biosensor based on plastic antibodies fo...

Carvalho, Margarida; Gomes, Rui; Rocha, Sandra Moreira; Barroca-Ferreira, Jorge; Maia, Claudio J.; Guillade, Lucía; Correa-Duarte, Miguel A.

STEAP1 is a cell surface protein of the STEAP family whose main function focuses on intercellular communication and cell growth. STEAP1 is considered a promising putative biomarker and a candidate target for prostate cancer treatment. For specific and selective detection of STEAP1, a molecularly imprinted polymers (MIP) was developed on a screen-printed electrode (C-SPE) whose surface was modified with a nanoco...


Development of a biosensor for phosphorylated Tau 181 protein detection in Earl...

Schneider, Maria; Guillade, Lucía; Correa-Duarte, Miguel A.; Moreira, Felismina

Alzheimer's disease (AD) is the most common form of dementia in the elderly, and there are still no reliable methods for its early detection. Recently, the phosphorylated protein Tau181 (p-Tau181) was identified as a highly specific biomarker for AD. Therefore, in this work, a new strategy for the development of an electrochemical-based immunosensor for the detection of p-Tau181 is described. For this purpose, ...


Development of a biosensor for phosphorylated Tau 181 protein detection in earl...

Schneider, Maria; Guillade, Lucía; Correa-Duarte, Miguel A.; Moreira, Felismina

Alzheimer's disease (AD) is the most common form of dementia in the elderly, and there are still no reliable methods for its early detection. Recently, the phosphorylated protein Tau181 (p-Tau181) was identified as a highly specific biomarker for AD. Therefore, in this work, a new strategy for the development of an electrochemical-based immunosensor for the detection of p-Tau is described. For this purpose, a c...


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