Introduction: Systemic sclerosis causes skin thickening, Raynaud’s phenomenon, visceral damage, and musculoskeletal issues. Hand impairment, affecting about 90% of patients, limits mobility, dexterity, and grip strength, significantly impacting daily life, with few treatment options. This study aims to characterize hand function in patients with Systemic Sclerosis and, secondarily, to describe those undergoing ...
Objectives: We aimed to identify clinical and serological predictors of myositis in mixed connective tissue disease (MCTD). Methods: We performed a nationwide, retrospective, multicentre study including adult-onset MCTD patients fulfilling at least one of the following diagnostic criteria: Sharp’s, Kasukawa, Alarcón-Segovia, or Kahn’s. Univariable analysis was performed using Chi-square, Fisher exact, Student’s...
Descreve-se a metodologia andragógica de aquisição de competências da unidade curricular de Conceção e Desenvolvimento de Sistemas de Informação (CDSI), envolvendo soluções tecnológicas digitais baseadas em casos de estudo reais. A abordagem metodológica, baseada na experimentação, por projeto, envolve análise de requisitos, modelação de processos de negócio e de software, especificação de testes, implementação...
O objetivo da missão Inteligência Artificial para a Administração Pública (IA>AP)* é promover a ligação entre estudantes, docentes e investigadores do Iscte, na área de Inteligência Artificial (IA), e as instituições da Administração Pública (AP). Pretende-se disponibilizar os conhecimentos e experiência académica na área de IA às entidades da AP que detêm dados passíveis de exploração, muitas vezes não usados,...
Introduction. Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide, usually not diagnosed until advanced stages of the disease. In Portugal, the Portuguese Burden of Obstructive Lung Disease (BOLD) study has estimated a prevalence of 14.2% in adults over 40 years, with 86.8% of under-diagnosis. The use of simple screening tools in Primary Health Care (PHC) can incre...
The quest for hard materials that are able to sustain elevated stresses as tools or cutting processes has led to the investigation of (Ti,Al)N/Mo multilayer coatings. These structures have been deposited by dc magnetron sputtering on high-speed steel and stainless-steel substrates and designed with modulation periods of approximately 13 nm, up to a total thickness of 2.8 [mu]m. Experimental X-ray diffraction (X...