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Rapid progression of CD8 and CD4 T cells to cellular exhaustion and senescence ...

Pedroso, Rodrigo B.; Torres, Lícia; Ventura, Lucas Araújo; Camatta, Giovanna Caliman; Mota, Catarina; Mendes, Ana Catarina; Ribeiro, Filipa

Risk factors for the development of severe COVID-19 include several comorbidities, but age was the most striking one since elderly people were disproportionately affected by SARS-CoV-2 infection. Among the reasons for this markedly unfavorable response in the elderly, immunosenescence and inflammaging appear as major drivers of this outcome. A finding that was also notable was that hospitalized patients with se...


Hypothyroidism does not lead to worse prognosis in COVID-19: findings from the ...

Pereira, Daniella Nunes; Silveira, Leticia Ferreira Gontijo; Guimarães, Milena Maria Moreira; Polanczyk, Carísi Anne; Nunes, Aline Gabrielle Sousa

Made available in DSpace on 2022-04-29T08:39:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: It is not clear whether previous thyroid diseases influence the course and outcomes of COVID-19. Methods: The study is a part of a multicentric cohort of patients with confirmed COVID-19 diagnosis from 37 hospitals. Matchi...

Date: 2022   |   Origin: Oasisbr

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