7 documents found, page 1 of 1
Preoperative diagnostic criteria for scleroatrophic gallbladder: A systematic r...
Bessa-Melo, R; Fernandes, C; Aguiar, A; Lopez-Ben, S; Guimarães, L; Serralheiro, PBackground Although scleroatrophic gallbladder is a rare condition, it presents significant clinical challenges in diagnosis and management. More agreement is needed on this disorder's diagnostic criteria and optimal management approach. We will conduct a systematic review to summarise the scleroatrophic gallbladder's preoperative diagnostic criteria, including imaging modalities. Methods A systematic review wi...
Awake examination versus DISE for surgical decision making in patients with OSA...
Certal, VF; Pratas, R; Guimarães, L; Lugo, R; Tsou, Y; Camacho, M; Capasso, ROBJECTIVE: Traditionally, upper airway examination is performed while the patient is awake. However, in the past two decades, drug-induced sleep endoscopy (DISE) has been used as a method of tridimensional evaluation of the upper airway during pharmacologically induced sleep. This study aimed to systematically review the evidence regarding the usefulness of DISE compared with that of traditional awake examinati...
Assessment of groundwater contamination in an agricultural peri-urban area (NW ...
Barroso, MF; Ramalhosa, MJ; Olhero, A; Antão, MC; Pina, MF; Guimarães, L; Teixeira, J; Afonso, MJ; Delerue-Matos, C; Chaminé, HIThe excessive use of pesticides and fertilisers in agriculture has generated a decrease in groundwater and surface water quality in many regions of the EU, constituting a hazard for human health and the environment. Besides, on-site sewage disposal is an important source of groundwater contamination in urban and peri-urban areas. The assessment of groundwater vulnerability to contamination is an important tool ...
Recomendações perioperatórias para profilaxia do tromboembolismo venoso no doen...
Amaral, C; Reis, J; Guimarães, L; Sá, AC; Moreto, A; Araújo, F; Guimarães, M; Felicíssimo, P; Teixeira, J; Fonseca, C; Miranda, LO propósito destas recomendações é fornecer uma ferramenta fundamentada na evidência científica atual, centrada no doente, que possa ser útil na prática clínica e que contribua para a implementação adequada, sistemática e transversal da profilaxia do tromboembolismo venoso no doente adulto. Foram aprovadas, com o apoio da Sociedade Portuguesa de Anestesiologia, por Consenso Nacional Multidisciplinar entre as es...
Molecular diagnosis of Huntington disease in Portugal: implications for genetic...
Costa, MC; Magalhães, P; Ferreirinha, F; Guimarães, L; Januário, C; Gaspar, I; Loureiro, L; Vale, J; Garrett, C; Regateiro, FJ; Magalhães, M; Sousa, AHuntington disease (HD) is a neurodegenerative, autosomal dominant disorder of late-onset, caused by the expansion of a CAG repeat in the coding region of the gene. Ours is the reference laboratory for genetic testing in HD, in Portugal, since 1998; 90.1% of all 158 families known were identified for the first time, including patients with unusual presentation or without family history. A total of 338 genetic t...
Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n alle...
Silveira, I; Miranda, C; Guimarães, L; Moreira, MC; Alonso, I; Mendonça, P; Ferro, A; Pinto-Basto, J; Coelho, J; Ferreirinha, F; Poirier, JBACKGROUND: Ten neurodegenerative disorders characterized by spinocerebellar ataxia (SCA) are known to be caused by trinucleotide repeat (TNR) expansions. However, in some instances the molecular diagnosis is considered indeterminate because of the overlap between normal and affected allele ranges. In addition, the mechanism that generates expanded alleles is not completely understood. OBJECTIVE: To examine the...
Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n alle...
Silveira, I; Miranda, C; Guimarães, L; Moreira, MC; Alonso, I; Mendonça, P; Ferro, A; Pinto-Basto, J; Coelho, J; Ferreirinha, F; Poirier, J; Vale, JBACKGROUND: Ten neurodegenerative disorders characterized by spinocerebellar ataxia (SCA) are known to be caused by trinucleotide repeat (TNR) expansions. However, in some instances the molecular diagnosis is considered indeterminate because of the overlap between normal and affected allele ranges. In addition, the mechanism that generates expanded alleles is not completely understood. OBJECTIVE: To examine the...