Objectives: This study aimed to investigate oral microbial signatures associated with hyperglycaemia, by correlating the oral microbiome with three glycaemic markers. Potential association between clinical parameters and oral bacterial taxa that could be modulating the hyperglycaemic microbiome was also explored. Methods: Twenty-three individuals diagnosed with type 2 Diabetes Mellitus (T2D) and presenting peri...
Este manual é fruto da união, amizade e dedicação de professores PhDs do Departamento de Odontologia da Faculdade de Ciências da Saúde da Universidade de Brasília (ODT/FS/UnB), alunos de Pós-graduação e extensionistas do “Projeto Saúde Bucal de Pacientes Portadores de Diabetes mellitus: Diagnóstico e Tratamento de Alterações Salivares, Doença Periodontal, Doenças Endodônticas e Cárie Dentária”. O projeto inicio...
Cardiovascular disease is the main cause of death in the contemporary western world and traditional risk factors do not completely explain its development. Plausible mechanisms have been proposed to explain the relationship between periodontal disease and cardiovascular disease, since both diseases present complex etiological factors, combining genetic and environmental influences. Several studies indicate that...
Recurrent aphthous stomatitis (RAS) is one of the commonest disorders of the oral mucosa, with the onset of recurring painful ulcer lesions typically occurring in childhood or adolescence. The disorder is divided into three clinical forms: ulcer minor, ulcer major and herpetiform ulcer, the first form being the commonest. The etiology remains undefined, but there are evidences of several predisposing factors an...
Objectives: The aim of this study was to analyze the periodontal parameters of patients with chronic renal failure. Material and Methods: The periodontal status of 16 Brazilian patients aged 29 to 53 (41.7±7.2) years with chronic renal failure (CRF) and another matched group of 14 healthy controls with periodontitis was assessed clinically and microbiologically. Probing pocket depth (PPD), gingival recession (G...
Phagocytosis by neutrophils and monocytes constitutes the main defense mechanism against bacterial challenges in periodontitis. Phagocytosis by neutrophils has already been evaluated, whereas phagocytic function of monocytes has hardly been addressed so far. Objectives: The aim of this study was to assess phagocytosis by neutrophils and monocytes in periodontitis. Material and Methods: The sample included 30 su...
A disciplina de Periodontia desenvolve, com o apoio de outras disciplinas do curso de Odontologia-UnB, o projeto de extensão “Atendimento periodontal em pacientes com diabetes mellitus tipo 1 e 2”. Atividades que articulam ensinopesquisa à extensão são desenvolvidas no projeto e propiciam aos participantes rica oportunidade de aprendizagem, vivência em pesquisa e, sobretudo, integração às comunidades atendidas....
OBJECTIVES: The purpose of this study was to evaluate the prevalence of alveolar bone loss (BL) in healthy children treated at private pediatric dentistry clinics in Brasília, Brazil. MATERIAL AND METHODS: The research included 7,436 sites present in 885 radiographs from 450 children. The BL prevalence was estimated by measuring the distance from the cementoenamel junction (CEJ) to alveolar bone crest (ABC). Da...
Objectives: This study assessed the bone density gain and its relationship with the periodontal clinical parameters in a case series of a regenerative therapy procedure. Material and Methods: Using a split-mouth study design, 10 pairs of infrabony defects from 15 patients were treated with a pool of bovine bone morphogenetic proteins associated with collagen membrane (test sites) or collagen membrane only (cont...