105 documents found, page 1 of 11

Neurological Complications of Diabetes Mellitus

Diabetes mellitus (DM) is a disease with a high global prevalence that can often lead to neurological complications. Involvement of the peripheral nervous system (PNS) by diabetes includes sensory-motor polyneuropathy (PNP), small fiber neuropathy, autonomic neuropathy, lumbosacral radiculoplexopathy, cranial neuropathies and compressive mononeuropathies. Regarding central nervous system (CNS) complications, th...

Status Epilepticus Amauroticus

Early retinal changes in type 2 diabetes detected by texture-based OCT analysis...

Background: Diabetic retinopathy (DR) is often diagnosed many years after diabetes onset, highlighting the need for early diagnosis. The current study aimed to assess whether texture analysis of computed optical coherence tomography (OCT) retinal images can identify (very) early retinal changes. We previously reported retinal texture changes in a type 1 diabetes animal model. This study extends this approach to...

Direct crosstalk between adult human retinas as suggested by interocular transf...

Crosstalk mechanisms between retinas were never documented in humans despite being documented for several other species, including non-human primates. Results of the first-in-human study that documents the crosstalk between retinas by measuring the vascular response in one retina to the photic stimulation of the contralateral eye in health and disease are reported herein. A stimulation apparatus was developed a...

Retinal OCT-derived texture features as potential biomarkers for early diagnosi...

PURPOSE. Diabetic retinopathy (DR) is usually diagnosed many years after diabetes onset. Indeed, an early diagnosis of DR remains a notable challenge, and, thus, developing novel approaches for earlier disease detection is of utmost importance. We aim to explore the potential of texture analysis of optical coherence tomography (OCT) retinal images in detecting retinal changes in streptozotocin (STZ)-induced dia...

Creutzfeldt-Jakob Disease: A Decade of Assistential Activity at Centro Hospital...

Introduction: Sporadic Creutzfeldt-Jakob disease (sCJD) is the most frequent of human prion diseases, with an estimated incidence of 1 case per million / habitants per year. Clinical manifestations include multidomain cognitive impairment with pyramidal, extrapyramidal and/or cerebellar signs. It is a rapidly progressive and fatal disease. Our aim was to do a sociodemographic, clinical and progression evaluatio...

Housing and inequality: the case of Portugal

Housing and Inequality: the case of Portugal

Numerous definitions of inequality exist, but at its core inequality refers to “the phenomenon of unequal and/or unjust distribution of resources and opportunities among members of a given society” (Koh, 2020:269), limiting the possibility for disadvantaged individuals or groups to benefit from certain opportunities in life (health, education, housing, etc.). In the fields of urban studies, sociology and geogra...

MedTech Simulator – A tool for medical students

Socioeconomic and health system progress has resulted in significant improvements in living conditions and an increase in average life expectancy. However, the aging of the European population highlights the growing demand for healthcare. Technology plays a crucial role in transforming this sector, driving advances in the treatment and diagnosis of diseases. Medical simulation emerges as an essential tool for i...

Home Assistive Robot for Alzheimer's Patients

With the increase in the senior population, especially patients with dementia and Alzheimer's, healthcare professionals are increasingly overwhelmed. Existing assistive technologies to improve these patients’ quality of life and their caregivers are scarce given the daily challenges they face. To tackle this issue, a domestic assistive robot was developed for Alzheimer's patients – AlzheimerAlly - which encompa...