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Development of a subcutaneous endometriosis rat model

Pereira, Francisco Edson Ximenes Gomes; Almeida, Paulo Roberto Carvalho de; Dias, Bruno Hállan Meneses; Vasconcelos, Paulo Roberto Leitão de

PURPOSE: To present a rat model of subcutaneous endometriosis for the study of pathophysiology and the effects of drugs. METHODS: Fifty three-month-old female Wistar rats (Rattus norvergicus) were distributed into one control group and four treatment groups: estradiol (2.5; 5; 10mg/kg sc), medroxyprogesterone acetate (0.5; 2; 5mg/kg sc), triptorelin pamoate (0.18; 0.56mg/kg sc) and acetylsalicylic acid (3mg/kg ...

Date: 2016   |   Origin: Oasisbr
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