11 documents found, page 1 of 2
Effects of alleles in crossbred pigs estimated for genomic prediction depend on...
Guimarães, Simone E. F.; Sevillano, Claudia A.; Napel, Jan ten; Silva, Fabyano F.; Calus, Mario P. L.This study investigated if the allele effect of a given single nucleotide polymorphism (SNP) for crossbred performance in pigs estimated in a genomic prediction model differs depending on its breed-of-origin, and how these are related to estimated effects for purebred performance.SNP-allele substitution effects were estimated for a commonly used SNP panel using a genomic best linear unbiased prediction model wi...
Genome-wide association studies for tick resistance in Bos taurus × Bos indicus...
Otto, Pamela I.; Guimarães, Simone E. F.; Verardo, Lucas L.; Azevedo, Ana Luísa S.; Sevillano, Claudia A.; Pires, Maria de Fatima A.Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to ...
In vitro evaluation of cryopreserved bovine sperm and its relation to field fer...
Okano, Denise S.; Penitente‐Filho, Jurandy M.; León, Victor E. Gomez; Maitan, Paula P.; Silveira, Camila O.; Waddington, Bruna; Díaz‐Miranda, Edgar A.This study aimed to assess characteristics of bovine cryopreserved sperm and evaluate its relation to field fertility in fixed‐time artificial insemination (FTAI). Semen samples of 16 bulls were used to inseminate 811 Nellore cows, and four of these bulls were also used to inseminate 101 Nellore heifers. Samples of the same ejaculate used for FTAI from each bull were analysed in the laboratory after thawing. Sp...
Weighted single-step GWAS and gene network analysis reveal new candidate genes ...
Marques, Daniele B. D.; Bastiaansen, John W. M.; Broekhuijse, Marleen L. W. J.; Lopes, Marcos S.; Knol, Egbert F.; Harlizius, BarbaraIn recent years, there has been increased interest in the study of the molecular processes that affect semen traits. In this study, our aim was to identify quantitative trait loci (QTL) regions associated with four semen traits (motility, progressive motility, number of sperm cells per ejaculate and total morphological defects) in two commercial pig lines (L1: Large White type and L2: Landrace type). Since the ...
Quantitative trait loci for carcass, internal organ and meat quality traits on ...
Paixão, Débora M.; Silva Filho, Miguel I. da; Pereira, Mário S.; Lopes, Marcos S.; Barbosa, Leandro; Souza, Katiene Régia Silva; Lopes, Paulo S.The objective of this study was to map quantitative trait loci (QTL) on porcine chromosomes 16, 17 and 18 and to determine their association with carcass, organ and meat quality traits. An F2 population was produced by crossing two boars of the naturalized Brazilian Piau breed with 18 commercial females (Landrace x Large White x Pietrain). The population was genotyped for 11 microsatellite markers distributed o...
Gene networks for total number born in pigs across divergent environments
Verardo, Lucas L.; Lopes, Marcos S.; Mathur, Pramod; Madsen, Ole; Silva1, Fabyano F.; Groenen, Martien A. M.; Knol, Egbert F.; Lopes, Paulo S.For reproductive traits such as total number born (TNB), variance due to different environments is highly relevant in animal breeding. In this study, we aimed to perform a gene-network analysis for TNB in pigs across different environments using genomic reaction norm models. Thus, based on relevant single-nucleotide polymorphisms and linkage disequilibrium blocks across environments obtained from GWAS, differen...
Use of multivariate analysis to evaluate genetic groups of pigs for dry-cured h...
Ventura, Henrique T.; Lopes, Paulo S.; Peloso, José V.; Guimarães, Simone E. F.; Carneiro, Antonio P. S.; Carneiro, Paulo L. S.Records of a pig population used for dry-cured ham production were used to evaluate genetic groups by multivariate analysis. The investigated genetic groups were as follows: DULL=Duroc×(Landrace×Large White), DULA=Duroc×Landrace, DUWI=Duroc×Large White, WIWI=Large White and DUDU=Duroc. Two groups were obtained for the carcass traits hot carcass weight (HCW), backfat thickness (BT) and loin depth (LD), with the ...
Molecular factors underlying the deposition of intramuscular fat and collagen i...
Martins, Taiane S.; Sanglard, Letícia M. P.; Silva, Walmir; Chizzotti, Mário L.; Rennó, Luciana N.; Serão, Nick V. L.; Silva, Fabyano F.Studies have shown that intramuscular adipogenesis and fibrogenesis may concomitantly occur in skeletal muscle of beef cattle. Thus, we hypothesized that the discrepancy of intramuscular fat content in beef from Nellore and Angus was associated with differences in intramuscular adipogenesis and fibrogenesis during the finishing phase. To test our hypothesis, longissimus muscle samples of Nellore (n = 6; BW = 37...
Revealing new candidate genes for reproductive traits in pigs: combining Bayesi...
Verardo, Lucas L.; Silva, Fabyano F.; Lopes, Marcos S.; Madsen, Ole; Bastiaansen, John W. M.; Knol, Egbert F.; Kelly, Mathew; Varona, LuisReproductive traits such as number of stillborn piglets (SB) and number of teats (NT) have been evaluated in many genome-wide association studies (GWAS). Most of these GWAS were performed under the assumption that these traits were normally distributed. However, both SB and NT are discrete (e.g. count) variables. Therefore, it is necessary to test for better fit of other appropriate statistical models based on ...
Identification of suitable reference genes for real time quantitative polymeras...
Nascimento, Carlos S.; Barbosa, Leandro T.; Brito, Claudson; Fernandes, Roberta P. M.; Mann, Renata S.; Pinto, Ana Paula G.; Oliveira, Haniel C.Thirteen reference genes were investigated to determine their stability to be used as a housekeeping in gene expression studies in skeletal muscle of chickens. Five different algorithms were used for ranking of reference genes and results suggested that individual rankings of the genes differed among them. The stability of the expression of reference genes were validated using samples obtained from the Pectoral...