6 documents found, page 1 of 1
OPHTHALMOLOGICAL EVALUATION OF SHEEP FROM THE ALENTEJO REGION -PORTUGAL
Guimarães, Tarcísio Guerra; Menezes Cardoso, Karla; Hadade, Ismail Ramalho; Marques Brito, Marta; Melo Oliveira, Manuela; Vilela Mamede, FabricioConsidering the importance of the flock of Alentejo sheep, the goal of this study was to determine the average values of eye examinations, evaluate the ophthalmoscopic features and fluorescein staining for Merino sheep from Alentejo region, in Portugal. The 48 eyes of 24 healthy, female sheep belonging to the sheep flock at the University of Évora were evaluated. The average values obtained for Schirmer tear te...
Localização subcelular do novo fotossensibilizador em células do melanoma ocula...
Guimarães, Tarcísio Guerra; Menezes Cardoso, Karla; Marto, Carlos Miguel; Teixo, Ricardo; Serambeque, Beatriz; Pereira, Nélson; Piñeiro, MartaIntrodução: O melanoma ocular é o objetivo de várias investigações em medicina e medicina veterinária devido à baixa taxa de resposta aos tratamentos conservadores convencionais1. A terapia fotodinâmica (PDT) é uma terapia mais conservadora para os tecidos não neoplásicos, que induz e ativa as vias de morte celular nos tecidos neoplásicos alvo2,3. O fotossensibilizador, luz e oxigenio são os três componentes vi...
OCULAR MELANOMA IN DOGS AND CATS: EPIDEMIOLOGICAL SURVEY IN PORTUGA
Guimarães, Tarcísio Guerra; Mamede, Fábio; Cardoso, Karla Menezes; Marto, Carlos; Caramelo, Francisco; Tasso, Gláuber; Andrade, Arthur; Alexandre, NunoPurpose: The epidemiology of ocular melanoma in dogs and cats in Portugal was assessed. Methods: Data collection was carried out through the distribution of an online questionnaire for veterinarians in Portugal. The survey covered the year 2018 and was made available for responses from 2019-2020. Results: 47 responses were obtained, representing 5.7% of there turn to the survey. A total of 32.61% of the profess...
IN VITRO PHOTODYNAMIC THERAPY ON OCULAR MELANOMA CELLS
Guimarães, Tarcísio Guerra; Carvalho, Gabriela; Mamede, Fabrício Vilela; Cardoso, Karla Menezes; Marto, Carlos Miguel; Piñeiro, MartaPurpose. To evaluate the effect of newly developed Ring-fused chlorins on cell proliferation of ocular melanoma. Methods. Human cell line MP-41 and a canine primary culture were subjected to the photosensitizers at concentrations between 0,5-1000 nM for 24 hours. The cells were irradiated with 10J (ƛ>570nm). Control groups included: untreated cells and cells submitted only to the administration vehicle (dimethy...
Current Therapeutics and Future Perspectives to Ocular Melanocytic Neoplasms in...
Guimarães, Tarcísio Guerra; Cardoso, Karla Menezes; Tralhão, Pedro; Marto, Carlos Miguel; Alexandre, Nuno; Botelho, Maria Filomena; Laranjo, MafaldaNeoplasms of melanocytic origin are diseases relevant to dogs and cats' ophthalmic oncology due to their incidence, potential visual loss, and consequent decrease in life quality and expectancy. Despite its non-specific clinical presentation, melanocytic neoplasms can be histologically distinguished in melanocytomas, which present benign characteristics, and malignant melanomas. The diagnosis often occurs in ad...
Clinical Aspects of Amniotic Membrane Implants in Corneal Repair in Dogs with C...
Rozin, Adriano; Cardoso, Karla Menezes; Guimarães, Tarcísio GuerraBackground: Among numerous disorders treated by veterinary ophthalmology, therapies employed to solve corneal ulcers stand out. Amniotic membrane transplantation is an effective surgical technique for the treatment of complicated corneal ulcers in the dog, with highly satisfactory visual and cosmetic outcomes. However, in veterinary ophthalmology, reports on the use of the amniotic membrane and its corneal reco...