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Minding your steps: a cross-sectional pilot study using foot-worn inertial sens...

Guimarães, V; Sousa, I; de Bruin, ED; Pais, J; Correia, MV

BackgroundCognitive impairment is a critical aspect of our aging society. Yet, it receives inadequate intervention due to delayed or missed detection. Dual-task gait analysis is currently considered a solution to improve the early detection of cognitive impairment in clinical settings. Recently, our group proposed a new approach for the gait analysis resorting to inertial sensors placed on the shoes. This pilot...


Using shoe-mounted inertial sensors and stepping exergames to assess the motor-...

Guimarães, V; Sousa, I; de Bruin, ED; Pais, J; Correia, MV

ObjectiveStepping exergames designed to stimulate physical and cognitive skills can provide important information concerning individuals' performance. In this study, we investigated the potential of stepping and gameplay metrics to assess the motor-cognitive status of older adults. MethodsStepping and gameplay metrics were recorded in a longitudinal study involving 13 older adults with mobility limitations. Gam...


The Impact of COVID-19 on Rare and Complex Connective Tissue Diseases: the Expe...

Talarico, R; Aguilera, S; Alexander, T; Amoura, Z; Antunes, A; Arnaud, L; Avcin, T; Beretta, L; Bombardieri, S; Burmester, G; Cannizzo, S; Cavagna, L

During the COVID-19 pandemic, the need to provide high-level care for a large number of patients with COVID-19 has affected resourcing for, and limited the routine care of, all other conditions. The impact of this health emergency is particularly relevant in the rare connective tissue diseases (rCTDs) communities, as discussed in this Perspective article by the multi-stakeholder European Reference Network on Ra...


Mixed Connective Tissue Disease: State of the Art on Clinical Practice Guidelines

Chaigne, B; Scirè, CA; Talarico, R; Alexander, T; Amoura, Z; Avcin, T; Beretta, L; Doria, A; Guffroy, A; Guimarães, V; Hachulla, É; Krieg, T; Launay, D

Mixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ribonucleoprotein particle. In this narrative review, we summarise the results of a systematic literature research which was performed ...


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