19 documents found, page 1 of 2
Treatment of the behavioral variant of frontotemporal dementia: a narrative review
Gambogi,Leandro Boson; Guimarães,Henrique Cerqueira; Souza,Leonardo Cruz de; Caramelli,PauloABSTRACT Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder accompanied by behavioral and personality changes and/or language deterioration. Its behavioral variant (bvFTD) is the main clinical presentation. Objective: This study aims to investigate the treatment alternatives for bvFTD available so far. Methods: We conducted a narrative review of bvFTD treatment options. We used PubMed and...
Behavioral variant frontotemporal dementia in patients with previous severe men...
Gambogi,Leandro Boson; Guimarães,Henrique Cerqueira; De Souza,Leonardo Cruz; Caramelli,PauloABSTRACT Objectives: To explore the relationship between severe/serious mental illness (SMI) and the behavioral variant of frontotemporal dementia (bvFTD), as the patterns of symptoms and cognitive performance that characterize both disorders share similarities. Methods: We performed a systematic review investigating what has already been published regarding the relationship between bvFTD and SMI. Studies were ...
Estrogen receptor-alpha gene XbaI A > G polymorphism influences short-term c...
Chaves,Amanda Caroline Silva; Fraga,Vanessa Gomes; Guimarães,Henrique Cerqueira; Teixeira,Antonio Lucio; Barbosa,Maira TonidandelABSTRACT This prospective study aimed to evaluate the influence of the -351A/G XbaI polymorphism in the estrogen receptor-alpha (ESR-1) gene on global cognitive scores of a community sample of healthy oldest-old individuals within one year of follow up. Methods The individuals were categorized in two groups according to the presence or absence of cognitive decline. Cognitive data were related to genetic informa...
Integrity of white matter structure is related to episodic memory performance i...
Resende,Elisa de Paula França; Tovar-Moll,Fernanda Freire; Ferreira,Fernanda Meireles; Bramati,Ivanei; Souza,Leonardo Cruz de; Carmona,Karoline CarvalhoABSTRACT The low-educated elderly are a vulnerable population in whom studying the role of white matter integrity on memory may provide insights for understanding how memory declines with aging and disease. Methods: Thirty-one participants (22 women), 23 cognitively healthy and eight with cognitive impairment-no dementia, aged 80.4 ± 3.8 years, with 2.2 ± 1.9 years of education, underwent an MRI scan with diffu...
Kraepelin’s description of chronic mania: a clinical picture that meets the beh...
Gambogi,Leandro Boson; Guimarães,Henrique Cerqueira; Daker,Maurício Viotti; Souza,Leonardo Cruz de; Caramelli,PauloABSTRACT Chronic mania is an under-investigated condition and few reports have associated this disorder with an organic background. The present work examines Kraepelin’s reliable description of chronic mania from a current behavioral neurology viewpoint. Kraepelin had described a cluster of symptoms that are now recognized as core manifestations of the behavioral variant frontotemporal dementia (bvFTD) clinical...
Influence of age on delayed surgical treatment of proximal femoral fractures
Gomes,Lisiane Pinto; Nascimento,Leandra Delfim do; Campos,Tulio Vinicius de Oliveira; Paiva,Edson Barreto; Andrade,Marco Antonio Percope deABSTRACTOBJECTIVE: To investigate the influence of patients' age on the delay between diagnosis and surgical treatment of proximal femoral fracturesMETHODS: This is a retrospective study, con-ducted at a tertiary university hospital, including all patients admitted with proximal femoral fractures between March 2013 and March 2014. The participants were categorized into four groups according to age levels. The g...
Features associated with cognitive impairment and dementia in a community-based...
Guimarães,Henrique Cerqueira; Cascardo,Jorge Luiz; Beato,Rogério Gomes; Barbosa,Maira Tonidandel; Machado,Thais Helena; Almeida,Mariana Alves deABSTRACT A higher level of educational attainment constitutes a protective factor against cognitive decline in the elderly. Nevertheless, the elements underpinning this association are yet not fully understood. Objective: The primary aim of this study was to compare cognitively impaired illiterate elderly subjects with cognitively preserved counterparts, according to demographics, comorbidities, lifetime habits...
Analysis of a case series of behavioral variant frontotemporal dementia: Emphas...
Guimarães,Henrique Cerqueira; Vale,Thiago Cardoso; Pimentel,Victor; de Sá,Nayara Carvalho; Beato,Rogério Gomes; Caramelli,PauloABSTRACT Introduction: Despite many advances in the characterization of the behavioral variant of frontotemporal dementia (bvFTD), the diagnosis of this syndrome poses a significant challenge, while delays or diagnostic mistakes may impact the proper clinical management of these patients. Objective: To describe the clinical profile at first evaluation of a sample of patients with bvFTD from a specialized outpat...
Functional profile of patients with behavioral variant frontotemporal dementia ...
Lima-Silva,Thais Bento; Bahia,Valéria Santoro; Carvalho,Viviane Amaral; Guimarães,Henrique Cerqueira; Caramelli,Paulo; Balthazar,MárcioABSTRACT There are few studies describing the functional changes in behavioral variant frontotemporal dementia (bvFTD) and it is not clear which aspects of functionality are affected by the disease. Objective: The aim of the present investigation was to characterize the functional profile of patients previously diagnosed with bvFTD. Methods: The sample consisted of 31 patients diagnosed with bvFTD, who were com...
Very late-onset behavioral variant frontotemporal dementia
Guimarães,Henrique Cerqueira; Espindola,Tatiana de CarvalhoABSTRACT Current concepts regarding frontotemporal lobar degeneration (FTLD) have evolved rapidly in recent years. Genetically determined FTLD cohorts have broadened our knowledge pertaining to its clinical presentation, neuroimaging findings and demographics. In this study we present a case report of a patient diagnosed with behavioral variant frontotemporal dementia diagnosis in her nineties during hospital a...