3 documents found, page 1 of 1
The patient profile of individuals with Alpha-1 antitrypsine gene mutations at ...
Felisbino,Manuela Brisot; Fernandes,Frederico Leon Arrabal; Nucci,Maria Cecília Nieves Maiorano de; Pinto,Regina Maria de Carvalho; Pizzichini,EmilioABSTRACT Objective: The clinical, functional, radiological and genotypic descriptions of patients with an alpha-1 antitrypsin (A1AT) gene mutation in a referral center for COPD in Brazil. Methods: A cross-sectional study of patients with an A1AT gene mutation compatible with deficiency. We evaluated the A1AT dosage and genotypic, demographic, clinical, tomographic, and functional characteristics of these patien...
Leicester Cough Questionnaire: translation to Portuguese and cross-cultural ada...
Felisbino,Manuela Brisot; Steidle,Leila John Marques; Gonçalves-Tavares,Michelle; Pizzichini,Marcia Margaret Menezes; Pizzichini,EmilioObjective: To translate the Leicester Cough Questionnaire (LCQ) to Portuguese and adapt it for use in Brazil. Methods: Cross-cultural adaptation of a quality of life questionnaire requires a translated version that is conceptually equivalent to the original version and culturally acceptable in the target country. The protocol used consisted of the translation of the LCQ to Portuguese by three Brazilian translat...
Determinação do componente inflamatório das doenças das vias aéreas através do ...
Moritz,Pablo; Steidle,Leila John Marques; Felisbino,Manuela Brisot; Kleveston,Túlia; Pizzichini,Marcia Margaret Menezes; Pizzichini,EmilioOBJETIVO: Avaliar a utilização e a influência da determinação do componente inflamatório das doenças das vias aéreas (inflamometria), através do exame do escarro induzido, nas decisões terapêuticas de um serviço terciário de pneumologia. MÉTODOS: Foram analisadas 151 amostras de escarro induzido de 132 pacientes consecutivamente referidos para indução de escarro com propósitos clínicos por cinco pneumologistas,...