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Bioavailability and Bioequivalence: Meaning, Origin and Scientific, Pharmaceuti...

Paixão, Paulo; Silva, Nuno Elvas; Lobato, Maria do Rosário; Guimarães Morais, José A.

This article intends to focus on the meaning, origin and use (scientific, pharmaceutical and regulatory) of the concepts underlying the following related terms: Bioavailability, Biogalenics and Bioequivalence. The aim is to provide a historical perspective on the evolution of these concepts in terms of improving their definitions, the underlying science and their acceptance and use by the scientific community, ...


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