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Preconditioning with L-alanyl-glutamine upon cerebral edema and hypocampus red ...

Vasconcelos, Paulo Roberto Cavalcante de; Guimarães, André Brito Bastos; Campelo, Marcio Wilker Soares; Vasconcelos, Paulo Roberto Leitão de

PURPOSE: To evaluate the effects of the dipeptide L-alanyl-glutamine (L-Ala-Gln) as a preconditioning agent to potentially promote reduction in the intensity of lesion or induction of resilience in rats subjected to global cerebral ischemia/reperfusion (I/R) injury. METHODS: Thirty-six male Wistar rats weighing 280-300g were randomly assigned to six groups (n=6). Groups Sham 1h and 24h were treated with saline ...

Date: 2016   |   Origin: Oasisbr
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