189 documents found, page 1 of 19
Testes rápidos de antigénio e efetividade da vacina contra a COVID-19 nos cuida...
Gómez, Verónica; Delaunay, Charlotte Laniece; Kissling, Esther; Verdasca, Nuno; Gomes, Licínia; Guiomar, Raquel; Machado, Ausenda; Rodrigues, Ana PaulaA disponibilização dos testes rápidos de antigénio (TRAg) permitiu que o diagnóstico de infeção por SARS-CoV-2 possa ser feito antes ou durante uma consulta médica. Este conhecimento pode condicionar a procura de cuidados e por outro lado, o Médico de Família (MF) pode ter informação sobre o estado de infeção antes do recrutamento do doente para os estudos de efetividade vacinal. Estudos com desenho de caso-con...
RSV-Bacterial Co-Infection Is Associated With Increased Illness Severity in Hos...
Torres, Ana Rita; Gaio, Vânia; Melo, Aryse; Lança, Miguel; Barreto, Marta; Lagoa Gomes, Licínia Isabel; Azevedo, Inês; Bandeira, Teresa; Lito, DavidDuring the autumn/winter respiratory syncytial virus (RSV) epidemics, bacterial co-infection is common and affects the disease severity. We aimed to understand the relationship between RSV-bacterial co-infections and clinical severity since the RSV seasonality change after COVID-19 pandemic. We conducted a prospective, sentinel surveillance study at 20 sites in Portugal in children under 2 years hospitalized wi...
Genetic and Epidemiological Insights Into Respiratory Syncytial Virus Infections
Lança, Miguel; Gaio, Vânia; Rodrigues, Ana Paula; Henriques, Camila; Gomes, Licínia; Dias, Daniela; Chasqueira, Maria-Jesus; Guiomar, RaquelFunding Information: Funding: The authors received no specific funding for this work. We gratefully acknowledge all data contributors, authors and their originating laboratories and the contribution of all physicians that collaborated in the VigiRSV network (VigiRSV network: Teresa Gouveia, Regina Viseu, Maria Zarcos, Ricardo Castro, Jorge Rodrigues, Virg\u00EDnia Martinez, Eurico Jorge Gaspar, Carlos Caldas, E...
Probe-based metagenomic pathogen detection: advancing laboratory capacity for c...
Ferreira, Rita; Coelho, Luís; Santos, João Dourado; Sobral, Daniel; Isidro, Joana; Mixão, Verónica; Pinto, Miguel; Nunes, Alexandra; Borrego, Maria JoséProbe-based pathogen enrichment, followed by NGS, is a promising tool for complex diagnosis, overcoming traditional challenges of shotgun metagenomics, namely small microbial/human genetic material ratio and demanding computational resources. Here, we assessed the combined detection performance of two Illumina probe-based panels, the Respiratory and the Urinary Pathogen ID panels (RPIP and UPIP), using 99 clini...
COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA...
Lanièce Delaunay, Charlotte; Martínez-Baz, Iván; Sève, Noémie; Domegan, Lisa; Mazagatos, Clara; Buda, Silke; Meijer, Adam; Kislaya, IrinaBackground: Scarce European data in early 2021 suggested lower vaccine effectiveness (VE) against SARS-CoV-2 Omicron lineages than previous variants. Aim: We aimed to estimate primary series (PS) and first booster VE against symptomatic BA.1/BA.2 infection and investigate potential biases. Methods: This European test-negative multicentre study tested primary care patients with acute respiratory symptoms for SAR...
BI-REAL: A 12-session DBT skills group intervention adapted for bipolar disorde...
Azevedo, Julieta Martins; Swales, Michaela; Carreiras, Diogo; Guiomar, Raquel; Macedo, António; Castilho, PaulaInternational guidelines endorse psychological treatment for Bipolar Disorder (BD); however, the absence of a recognised gold-standard intervention requires further research. A Dialectical Behaviour Therapy (DBT) skills group intervention with 12 sessions was developed. This pilot randomised controlled trial (RCT) aims to evaluate the feasibility, acceptability, and outcomes variance of Bi-REAL – Respond Effect...
Benchmarks for dialectical behavioural therapy intervention in adults and adole...
Azevedo, Julieta Martins; Carreiras, Diogo; Hibbs, Caitlin; Guiomar, Raquel; Osborne, Joshua; Hibbs, Richard; Swales, MichaelaDialectical Behaviour Therapy (DBT) is a multi-component cognitive behavioural intervention with proven efficacy in treating people with borderline personality disorder symptoms. Establishing benchmarks for DBT intervention with both adults and adolescents is essential for bridging the gap between research and clinical practice, improving teams' performance and procedures.
Validation of the Bipolar Recovery Questionnaire for the Portuguese Population:...
Azevedo, Julieta; Carreiras, Diogo; Guiomar, Raquel; Martins, Maria João; Macedo, António; Castilho, PaulaIntroduction: The paradigm in mental health care is progressively moving towards a recovery-focused perspective. Thus, there is a need for validated instruments to measure recovery in bipolar disorder (BD). The Bipolar Recovery Questionnaire (BRQ) is the most used instrument to assess it. The aim of this study was to translate and perform a cross-cultural adaptation of the BRQ to European Portuguese (PT-PT) and...
Programa Nacional de Vigilância da Gripe: relatório da época 2023/2024
Guiomar, Raquel; Verdasca, Nuno; Gomes, Licínia; Henriques, Camila; Dias, Daniela; Lança, Miguel; Rodrigues, Ana Paula; Silva, Susana Pereira daRelatório anual do Programa Nacional de Vigilância da Gripe e de Outros Vírus Respiratórios (PNVG), que descreve a caraterização clínica e laboratorial da atividade gripal na época 2023/2024. O PNVG assegura a vigilância epidemiológica da gripe em Portugal, integrando as componentes de vigilância clínica e laboratorial. A componente clínica possibilita descrever a intensidade e evolução da epidemia no tempo. A ...
Vigilância epidemiológica de infeções respiratórias: um estudo-piloto da adapta...
Gómez, Verónica; Guiomar, Raquel; Machado, Ausenda; Rodrigues, Ana PaulaA investigação epidemiológica de surtos de infeções respiratórias graves é determinante para a rápida identificação de ameaças à saúde pública. As infeções respiratórias de origem animal têm sido frequentemente reportadas nos últimos anos, incluindo gripe aviária, suína e mais recentemente em felinos e gado bovino. Após um surto de Influenza A(H5N1) em gatos na Polónia, em 2023, e em aves em Portugal desde nove...