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Stanozolol induces ventricular dysfunction by decreasing phospholamban phosphor...

Andrade, Tadeu Uggere de; Dubois Fillho, Dionisio; Silva, Cristiane Lyrio da; Silva, Mirian de Almeida; Almeida, Simone Alves de

Stanozolol is a steroid that causes lipid deposition in LDLr-/- mice, although the mechanism by which this dyslipidemia results in cardiac dysfunction is little understood. The aim of this study was to evaluate the effect of stanozolol on cardiac contractility and the participation of myocardial phospholamban (pPLB) phosphorylation in an atherosclerosis mouse model. LDL receptor knockout mice (LDLr-/-) were fed...

Data: 2022   |   Origem: Oasisbr

Chronic treatment with juçara (Euterpe edulis) fruit pulp produces antihyperten...

Puppin, Augusto Altoé; Silva, Cristiane Lyrio da; Ronchi, Silas Nascimento; Silva, Mirian de Almeida; Lima, Ewelyne Miranda de; Oliveira, Bruno Gomes de

Background: Juçara açaí is a Brazilian berry with high anthocyanidin content and high antioxidant properties. A correlation between oxidative stress, hypertension and baroreflex impairment is known, however, no previous studies investigate the effect of juçara fruit pulp on hypertension. Aim: The aim of this study was to investigate antihypertensive effect of juçara (Euterpe edulis) fruit pulp in SHR animals, i...

Data: 2022   |   Origem: Oasisbr

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