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Venomics and antivenomics of Bothrops erythromelas from five geographic populat...

Jorge, Roberta Jeane B.; Monteiro, Helena S. A.; Machado, Larissa Gonçalves; Guarnieri, Míriam C.; Ximenes, Rafael M.; Nojosa, Diva M. Borges

The Caatinga lancehead, Bothrops erythromelas, is a medically relevant species, responsible for most of the snakebite accidents in most parts of its distribution range in northeastern Brazil. The spectrum and geographic variability of its venom toxins were investigated applying a venomics approach to venom pools from five geographic areas within the Caatinga ecoregion. Despite its wide habitat, populations of B...

Date: 2021   |   Origin: Oasisbr

Structural basis for phospholipase A2-like toxin inhibition by the synthetic co...

Salvador, Guilherme H. M. [UNESP]; Gomes, Antoniel A. S. [UNESP]; Bryan-Quirós, Wendy; Fernández, Julián; Lewin, Matthew R.; Gutiérrez, José María

Made available in DSpace on 2020-12-12T01:05:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; The World Health Organization recently listed snakebite envenoming as a Neglected Tropical Disease, proposing strategies to significantly reduce the global burden of this complex pathology by 2030. In this context, effective adjuvant treatments to complement conventional antivenom therapy based on inhib...

Date: 2020   |   Origin: Oasisbr

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