3 documents found, page 1 of 1
Spectral and computational features of the binding between riparins and human s...
Camargo, Cintia Ramos [UNESP]; Caruso, Ícaro Putinhon [UNESP]; Gutierrez, Stanley Juan Chavez; Fossey, Marcelo Andres [UNESP]; Filho, José Maria BarbosaMade available in DSpace on 2018-12-11T17:14:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-05; The green Brazilian bay leaf, a spice much prized in local cuisine (Aniba riparia, Lauraceae), contains chemical compounds presenting benzoyl-derivatives named riparins, which have anti-inflammatory, antimicrobial and anxiolytic properties. However, it is unclear what kind of interaction riparins perfor...
Anticonvulsant property of N-salicyloyltryptamine: evidence of enhance of centr...
Quintans-Júnior, Lucindo José; Silva, Davi Alves da; Quintans, Jullyana de Souza Siqueira; Araújo, Adriano Antunes de Souza; Guimarães, Adriana GibaraAIM: In the present study we verified the anticonvulsant properties of the new tryptamine analogue, N-salicyloyltryptamine (NST), in rodents. METHODS AND RESULTS: In the evaluation of the anticonvulsant activity, NST protected the animals from the incidence of seizures induced by pentylenetetrazole (PTZ) and picrotoxin (PIC), in doses of 100 and 200 mg/kg. NST (100 and 200 mg/kg, i.p.) significantly eliminated ...
Bioassay-guided evaluation of antinociceptive effect of N-salicyloyltryptamine:...
Quintans-Júnior, Lucindo José; Silva, Davi Antas; Quintans, Jullyana de Souza Siqueira; Araújo, Adriano Antunes de Souza; Siqueira, Rosana de SouzaWe investigated the antinociceptive and nerve excitability effects of the N-salicyloyltryptamine (NST) NST-treated mice exhibited a significant decrease in the number of writhes when 100 and 200 mg/kg (i.p.) were administered (i.p.). This effect was not antagonized by naloxone (1.5 mg/kg, i.p.). NST inhibited the licking response of the injected paw when 100 and 200 mg/kg were administered (i.p.) to mice in the...