9 documents found, page 1 of 1
Ptosis in human immunodeficiency virus-infected patients under long-term antire...
Santos Silva, C; Nunes Vicente, B; Martins, B; Fonseca, AC; Coelho, P; Roque, R; Cota de Medeiros, F; Oliveira Santos, M; de Carvalho, MObjective: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. Methods: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a comprehensive diagnostic evaluation, including imaging studies, neurophysiological testing, muscle biopsy, and genetic analysis. A literature review was conducted. Results: On clinical exam...
Cognitive impairment and markers of optical neurodegeneration in early multiple...
Silva, R; Coelho, P; Seabra, M; Laranjinha, I; Vieira, D; Costa, O; Jesus, J; Fonseca, AC; Costa, S; Ferreira, I; Lemos, J; Sousa, C; Vale, J; Sá, MJIntroduction: Cognitive impairment and retinal atrophy have been proposed as two potential markers of neurodegeneration in multiple sclerosis (MS). We aimed at assessing the relation between peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell layer (mGCL) atrophy and cognitive performance in early MS. Methods: This is a multicenter cross-sectional study on patients with early MS (clinicall...
Early EEG Predicts Poststroke Epilepsy
Bentes, C; Martins, H; Peralta, AR; Morgado, C; Casimiro, C; Franco, AC; Fonseca, AC; Geraldes, R; Canhão, P; Pinho e Melo, T; Paiva, T; Ferro, JObjective: Electroencephalography (EEG) can identify biomarkers of epileptogenesis and ictogenesis. However, few studies have used EEG in the prediction of poststroke seizures. Our primary aim was to evaluate whether early EEG abnormalities can predict poststroke epilepsy. Methods: A prospective study of consecutive acute anterior circulation ischemic stroke patients, without previous epileptic seizures, who we...
Quantitative EEG and Functional Outcome Following Acute Ischemic Stroke
Bentes, C; Peralta, AR; Viana, P; Martins, H; Morgado, C; Casimiro, C; Franco, AC; Fonseca, AC; Geraldes, R; Canhão, P; Pinho e Melo, T; Paiva, TObjective: To identify the most accurate quantitative electroencephalographic (qEEG) predictor(s) of unfavorable post-ischemic stroke outcome, and its discriminative capacity compared to already known demographic, clinical and imaging prognostic markers. Methods: Prospective cohort of 151 consecutive anterior circulation ischemic stroke patients followed for 12 months. EEG was recorded within 72 h and at discha...
Laterality of Pneumonia in Acute Stroke
Alves, P; Silva, C; Baptista, J; Lima, B; Jacinto, M; Trigueiros, F; Martins, A; Melo, T; Fonseca, ACBACKGROUND/AIMS: Previous studies demonstrated an alteration of diaphragmatic excursion on the paretic side after stroke; however, it is unclear if this change has clinical repercussions. We aimed to determine if there was an association between the paretic side and the laterality of pneumonia after stroke. METHODS: A retrospective analysis of a consecutive cohort of patients admitted to a stroke unit from 2008...
Post-Stroke Seizures Are Clinically Underestimated
Bentes, C; Martins, H; Peralta, AR; Casimiro, C; Morgado, C; Franco, AC; Fonseca, AC; Geraldes, R; Canhão, P; Pinho e Melo, T; Paiva, T; Ferro, JMCerebrovascular disease is the leading cause of epilepsy in adults, although post-stroke seizures reported frequency is variable and few studies used EEG in their identification. To describe and compare EEG and clinical epileptic manifestations frequency in patients with an anterior circulation ischaemic stroke. Prospective study of acute anterior circulation ischaemic stroke patients, consecutively admitted to...
Seizures, Electroencephalographic Abnormalities, and Outcome of Ischemic Stroke...
Bentes, C; Peralta, AR; Martins, H; Casimiro, C; Morgado, C; Franco, AC; Viana, P; Fonseca, AC; Geraldes, R; Canhão, P; Pinho E Melo, T; Paiva, TOBJECTIVE: Seizures and electroencephalographic (EEG) abnormalities have been associated with unfavorable stroke functional outcome. However, this association may depend on clinical and imaging stroke severity. We set out to analyze whether epileptic seizures and early EEG abnormalities are predictors of stroke outcome after adjustment for age and clinical/imaging infarct severity. METHODS: A prospective study ...
Language Improvement One Week After Thrombolysis in Acute Stroke
Martins, IP; Fonseca, J; Morgado, J; Leal, G; Farrajota, L; Fonseca, AC; Melo, TPOBJECTIVES: Language recovery following acute stroke is difficult to predict due to several evaluation factors and time constraints. We aimed to investigate the predictors of aphasia recovery and to identify the National Institute of Health and Stroke Scale (NIHSS) items that best reflect linguistic performance, 1 week after thrombolysis. MATERIALS AND METHODS: We retrieved data from a prospective registry of p...
Peripheral Nerve Regeneration: Current Status and New Strategies Using Polymeri...
Pinho, AC; Fonseca, AC; Serra, AC; Santos, JD; Coelho, JFJExperiments concerning peripheral nerve regeneration have been reported since the end of the 19(th) century. The need to implement an effective surgical procedure in terms of functional recovery has resulted in the appearance of several approaches to solve this problem. Nerve autograft was the first approach studied and is still considered the gold standard. Since autografts require donor harvesting, other stra...