2 documents found, page 1 of 1
A modified progressive supranuclear palsy rating scale
Grötsch, Marie‐Therese; Respondek, Gesine; Colosimo, Carlo; Compta, Yaroslau; Corvol, Jean Christophe; Ferreira, Joaquim J; Huber, Meret KoroniBackground: The Progressive Supranuclear Palsy Rating Scale is a prospectively validated physician-rated measure of disease severity for progressive supranuclear palsy. We hypothesized that, according to experts' opinion, individual scores of items would differ in relevance for patients' quality of life, functionality in daily living, and mortality. Thus, changes in the score may not equate to clinically meanin...
A critique of the second consensus criteria for multiple system atrophy
Stankovic, Iva; Quinn, Niall; Vignatelli, Luca; Antonini, Angelo; Berg, Daniela; Coon, Elizabeth; Cortelli, Pietro; Fanciulli, AlessandraMultiple system atrophy (MSA) is an adult-onset progressive neurodegenerative disorder that manifests clinically with autonomic failure, parkinsonism, and ataxia in any combination. Oligodendroglial cytoplasmatic inclusions consisting of misfolded α-synuclein are a pathological hallmark of disease. The clinical diagnosis of MSA is typically delayed as a result of incomplete or nonspecific manifestations during ...