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Hydrazones in anion transporters: the detrimental effect of a second binding site

Martínez-Crespo, Luis; Halgreen, Lau; Soares, Márcio; Marques, Igor; Félix, Vítor; Valkenier, Hennie

Synthetic anion transporters can be developed using anion receptors that are able to bind the anion and stabilize it in the lipophilic interior of a bilayer membrane, and they usually contain functional groups with acidic NHs, such as ureas, thioureas and squaramides. To assess the suitability of acylhydrazones as a new functional group for the preparation of anion transporters, we have studied a family of thio...

Date: 2021   |   Origin: RIA - Repositório Institucional da Universidade de Aveiro
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