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Pollen and Spore Monitoring in the World. Clinical and Translational Allergy

Buters, Jeroen TM; Antunes, Célia M; Galveias, Ana; Bergmann, Karl C; Thibaudon, Michel; Galán, Carmen; Schmidt-Weber, Carsten; Oteros, Jose

Background Ambient air quality monitoring is a governmental duty that is widely carried out in order to detect non-biological (“chemical”) components in ambient air, such as particles of < 10 µm (PM10, PM2.5), ozone, sulphur dioxide, and nitrogen oxides. These monitoring networks are publicly funded and air quality data are open to the public. The situation for biological particles that have detrimental effects...


FoxP3, GATA-3 and T-bet expression in elderly asthma

Vale-Pereira, Sofia; Todo-Bom, Ana; Geraldes, Luisa; Schmidt-Weber, Carsten; Akdis, Cesmi; Mota-Pinto, Anabela

Background Asthma is a chronic inflammatory disorder in which Th2, Th1 and suppressive T cells (Tregs) play a role. The transcription factor FoxP3 plays a role in Treg differentiation hile T-bet is important for Th1 and GATA-3 for Th2 differentiation from naïve T cells. Recent data show that age-related deregulation of Treg cells is a mechanism of senescence affecting several chronic diseases. It is crucial to ...


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