Inflammation is a complex and tightly regulated process by a cascade of events that involves the production of prostaglandins (PG) by the inducible isoform cyclooxygenase 2 (COX-2) and the production of reactive pro-oxidant species. Conversely, COX-1, which is consistently present in a variety of tissues, has traditionally been categorized as the primary isoform responsible for maintaining the balance of prosta...
Background: Myxozoans are widespread cnidarian parasites that mostly infect fish and annelids as temporary and definitive hosts, respectively [1]. Mullets are a diverse fish group, which ubiquitous nature leaves vulnerable to parasitic infections [2]. Objective: This study aimed to acknowledge the myxozoan diversity infecting thicklip grey mullet Chelon labrosus in the Douro River estuary in northern Portugal. ...
Background: Myxosporeans are important fish endoparasites with a complex life cycle that involves the production of actinospores in annelid hosts. More than 2,400 myxosporean species are presently known, yet only about 60 have their complete life cycle described [1]. Difficulties in the annelid sampling and examination, namely from the marine environment, and typically low prevalence of infection, hinder our kn...
The aim of this study was a detailed chemical characterisation of the particles released during the preparation of popular Portuguese dishes. PM2.5 samples were collected from the exhaust stacks on the roofs of a university canteen, a charcoal-grilled chicken restaurant and a wood-oven roasted piglet restaurant. The speciation of organic compounds was carried out by gas chromatography-mass spectrometry. The can...
The main objective of this study was to evaluate the effect of two different drying methods on physicochemical characteristics and antioxidant activity of different Brassica spp. cultivars in order to produce a dietary flour. Fresh cabbages were subjected to two drying methods: convective air-drying (80 °C, during 2h with the previous blanching) and freeze-drying. An increase in crude protein, carbohydrates and...
Bupropion is an atypical antidepressant with a unique aminoketone structure similar to amphetamines. A narrow therapeutic margin is evident from observational studies that show seizure activity with doses of 400-600 mg or higher. A 38-year old woman took an overdose of 6 grams of bupropion with 110 grams of alcohol. She presented to the Emergency Department with agitation, visual hallucinations and myoclonus of...
The present article is intended to evaluate the quality of training and initial vocational qualification of young people, of professional courses secondary levels, with school accreditation and professional qualification of level IV. In that sense, it´s intended to know the perspective of students of professional courses in various areas of knowledge, their perceptions and expectations about the quality observe...
Stress-vulnerability models of schizophrenia have long suggested that multiple confluent variables influence disease outcome, including individual vulnerability and environmental factors (Nuechterlein & Dawson 1984). In general, people with schizophrenia tend to employ poor problem-solving strategies, are more likely to adopt passive coping styles, tend to use fewer types of coping strategies and have a propens...