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The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anophele...

Bahia, Ana Cristina; Kubota, Marina S.; Tempone, Antônio Jorge; Araújo, Helena R. C.; Guedes, Bruno A. M.; Orfanó, Alessandra Silva

Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and Plasmodium vivax is responsible for the majority of malaria cases in the Americas. Insects possess a powerful immune system to combat infections. Three pathways control the insect immune response: Toll, IMD, and JAK-STAT. Here we analyze the immune role o...

Date: 2020   |   Origin: Oasisbr
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