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The complete genome sequence of Chromobacterium violaceum reveals remarkable an...

Vasconcelos, Ana Tereza; De-Almeida, Darcy Fontoura; Hungría, Mariangela; Guimarães, Cláudia Teixeira; Antônio, Regina Vasconcellos

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spre...

Date: 2020   |   Origin: Oasisbr

Nasal vaccination with attenuated Salmonella expressing VapA: TLR2 activation i...

Cardoso, Silvia Almeida; Oliveira, Aline Ferreira; Ruas, Luciana Pereira; Trevisani, Marcel Montels; Oliveira, Leandro Licursi De; Hanna, Ebert Seixas

Virulent strains of Rhodococcus equi have a large plasmid of 80–90 kb, which encodes several virulence-associated proteins (Vap), including VapA, a lipoprotein highly associated with disease. We have previously demonstrated that oral immunisation with attenuated Salmonella enterica Typhimurium strain expressing the antigen VapA (STM VapA+) induces specific and long-term humoral and cellular immunity against R. ...

Date: 2018   |   Origin: Oasisbr


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