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Sensitivity of different DNA extraction methods and PCR to detect resistance in...
Sevilha-Santos, Lais; Aquino, Danielle Costa; Hans Neto, Günter; Costa, Fabiano José Queiroz; Sousa, Carlos Augusto Felipe de; Morelo, Elaine FariaIntroduction: Antimicrobial resistance in leprosy is an emerging problem, and the quantitative impact of low bacilloscopic indexes (BIs) on the sensitivity of molecular tests is unknown. We aimed to evaluate the sensitivity of gene sequencing for the detection of mutations related to antimicrobial resistance in Mycobacterium leprae in patients with low BIs using an analytical model. Methods: Patients with lepro...
Data: 2022
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Origem: Oasisbr