3 documents found, page 1 of 1

Is it acceptable to use animals to model obese humans? - A critical discussion ...

Animal use in medical research is widely accepted on the basis that it may help to save human lives and improve their quality. Recently, however, objections have been made specifically to the use of animals in scientific investigation of human obesity. This paper discusses two arguments for the view that this form of animal use, unlike some other forms of animal-based medical research, cannot be defended. The f...

Validating animal models for preclinical research: a scientific and ethical dis...

The use of animals to model humans in biomedical research relies on the notion that basic processes are sufficiently similar across species to allow extrapolation. Animal model validity is discussed in terms of the similarity between the model and human condition it is intended to model, but no formal validation of models is applied. There is a stark contrast here with non-animal alternatives in toxicology and ...

Ethics and refinement in animal research