4 documents found, page 1 of 1
Controlling Macrophage Polarization to Modulate Inflammatory Cues Using Immune-...
Almeida, A. F.; Miranda, M. S.; Vinhas, Carla Adriana Araújo; Gonçalves, A I; Gomes, Manuela E.; Rodrigues, Márcia T.The persistence of inflammatory mediators in tissue niches significantly impacts regenerative outcomes and contributes to chronic diseases. Interleukin-4 (IL4) boosts pro-healing phenotypes in macrophages (MÏ ) and triggers the activation of signal transducer and activator of transcription 6 (STAT6). Since the IL4/STAT6 pathway reduces MÏ responsiveness to inflammation in a targeted and precise manner, IL4 del...
Remote triggering of TGF-β/Smad2/3 signaling in human adipose stem cells laden ...
Matos, A. M.; Gonçalves, A. I.; Rodrigues, M. T.; Miranda, M. S.; Haj, A. E.; Reis, R. L.; Gomes, Manuela E.Injuries affecting load bearing tendon tissues are a significant clinical burden and efficient treatments are still unmet. Tackling tendon regeneration, tissue engineering strategies aim to develop functional substitutes that recreate native tendon milieu. Tendon mimetic scaffolds capable of remote magnetic responsiveness and functionalized magnetic nanoparticles (MNPs) targeting cellular mechanosensitive recep...
Cellular immunity in Holstein cows seropositive for Bovine Leukosis Virus (BLV)...
Gomes, V.; Baldacim, V. A. P.; Costa, J. F. R.; Costa e Silva, C. P.; Arcaro, J. R. P.; Miranda, M. S.; Sousa, R. S.; Fagliari, J. J. [UNESP]Made available in DSpace on 2018-11-29T05:57:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-01. Added 1 bitstream(s) on 2021-07-15T14:31:49Z : No. of bitstreams: 1 S0102-09352017000601367.pdf: 604874 bytes, checksum: e58a8f755a0c54a8c1ecd22eae20a2dc (MD5); This research evaluated the dynamics of leukocytes and lymphocytes subsets in seropositive Holstein cows for BLV during the transition period. ...
Thermochemical and Theoretical Studies of 2-Hydroxyquinoxaline, 2,3-Dihydroxyqu...
Ribeiro da Silva, M. A. V.; Matos, M. A. R.; Rio, Carolina; Miranda, M. S.; Morais, V. M. F.The standard (p° = 0.1 MPa) molar enthalpies of formation for crystalline 2-hydroxyquinoxaline, 2,3-dihydroxyquinoxaline, and 2-hydroxy-3-methylquinoxaline were derived from the standard molar enthalpies of combustion, in oxygen, at T = 298.15 K, measured by static bomb combustion calorimetry. The standard molar enthalpies of sublimation, at T = 298.15 K, of the three compounds were measured by Calvet microcalo...