8 documents found, page 1 of 1
Non-invasive bladder cancer detection: identification of a urinary volatile bio...
Carapito, Â.; Ferreira, V. S. Fernandes; Ferreira, A. C. Silva; Teixeira-Marques, A.; Henrique, R.; Jerónimo, C.; Roque, A. C. A.; Carvalho, F.Early detection of bladder cancer (BC) remains a major clinical challenge due to the limitations of current diagnostic methods, which are often invasive, expensive, or insufficiently sensitive, particularly for early-stage disease. Metabolomics approaches, when integrated with machine learning (ML) techniques, offer a powerful platform for identifying novel, non-invasive biomarkers. In this study, urinary volat...
Spectroscopic detection of pigments in tissues: correlation with tissue aging a...
Oliveira, Luís M.; Goncalves, T. M.; Botelho, A. R.; Martins, I. S.; Silva, H. F.; Carneiro, I.; Carvalho, S.; Henrique, R.; Tuchin, V. V.The direct calculation of the absorption coefficient spectra of various tissues from spectral measurements allowed to retrieve the contents of melanin and lipofuscin. In the rabbit brain cortex, 1.8 times higher melanin content is explained by the neuron degeneration process. Similar melanin and lipofuscin contents were found in the rabbit pancreas as a result of the tissue aging process. The conversion of 83 %...
Comparação e otimização de métodos de extração de DNA de células cervicais colh...
Silva, Andreia; Salta, S.; Henrique, R.; Jerónimo, C.O cancro do colo do útero é o nono cancro mais incidente nas mulheres em Portugal. O rastreio desta neoplasia tem evoluído desde a citologia convencional até à deteção do Vírus do Papiloma Humano em colpocitologia cervico-vaginal em meio líquido. Atualmente, novos marcadores biomoleculares, como alterações na metilação do ácido desoxirribonucleico (DNA), têm sido estudados como meio de triagem de mulheres infet...
Evaluation of prostate cancer volatilome: an in vitro approach
Lima, A.R.; Araújo, A.M.; Pinto, J.; Jerónimo, C.; Henrique, R.; Bastos, M.D.L.; Carvalho, Márcia; Guedes de Pinho, Paula
Visceral Obesity and Metabolic Syndrome Are Associated with Well-Differentiated...
Santos, A.; Santos, A.; Castro, C.; Raposo, L.; Pereira, S.; Torres, I.; Henrique, R.; Cardoso, H.; Monteiro, M.The determinants for gastroenteropancreatic neuroendocrine tumors (GEP-NET) recent burden are matters of debate. Obesity and metabolic syndrome (MetS) are well established risks for several cancers even though no link with GEP-NETs was yet established. Our aim in this study was to investigate whether well-differentiated GEP-NETs were associated with obesity and MetS. Patients with well-differentiated GEP-NETs (...
Renal cell carcinoma detection by analysis of volatile organic compounds in urine
Guedes de Pinho, Paula; Monteiro, M.; Moreira, N.; Jerónimo, C.; Henrique, R.; Bastos, M.; Gil, A.; Carvalho, Márcia
Exploratory urinary metabolomic profiling of renal cell carcinoma using H-1 NMR...
Monteiro, M.; Barros, A.; Carvalho, M.; Pires-Luis, A. S.; Jeronimo, C.; Henrique, R.; Maria de Lourdes, B.; Gil, A.; Guedes de Pinho, P.
A multicenter validation of an endoscopic classification with narrow band imagi...
Nunes, P. Pimentel; Ribeiro, M. Dinis; Soares, João Bruno; Pinto, R. Marcos; Santos, C.; Rolanda, Carla; Bastos, R. P.; Areia, M.; Afonso, L.BACKGROUND AND STUDY AIM: The reliability and external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim of the current study was to describe and estimate the accuracy and reliability of a simplified classification system for NBI in the diagnosis of gastric lesions. METHODS: Consecutive patients undergoing NBI endoscopy at two reference centers (n=85, 33% with dy...