12 documents found, page 1 of 2
Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor acti...
Pinto, P.; Machado, C.M.; Moreira, J.; Almeida, J.D.P.; Silva, P.M.A.; Henriques, A.C.; Soares, J.X.; Salvador, J.A.R.; Afonso, C.; Pinto, M.This study describes the synthesis of a series of chalcones, including pyrazole and a,b-epoxide de- rivatives, and evaluation of their cell growth inhibitory activity in three human tumor cell lines, as well as their lipophilicity using liposomes as a biomimetic membrane model. Structure-activity and structure- lipophilicity relationships were established for the synthetized chalcones. From this work, nine chal...
Depression and anxiety in living kidney donation: evaluation of donors and reci...
Lopes, A.; Frade, I.C.; Teixeira, L.; Oliveira, C.; Almeida, M.; Dias, L.; Henriques, A.C.Transplant Proc. 2011 Jan-Feb;43(1):131-6. Depression and anxiety in living kidney donation: evaluation of donors and recipients. Lopes A, Frade IC, Teixeira L, Oliveira C, Almeida M, Dias L, Henriques AC. SourceLyaison-Psychiatry and Health Psychology Unit, Oporto Hospital Centre, Oporto, Portugal. lopealice@gmail.com Abstract BACKGROUND: Psychosocial status of donors before and after living kidney donor trans...
Perceptions in Living Kidney Donation: What ProtagonistsThink and Feel
Frade, I.C.; Lopes, A.; Teixeira, L.; Rodrigues, J.; Almeida, M.; Dias, L.; Henriques, A.C.Abstract Background Although donor perceptions of donation have been evaluated in several programs, evaluation of associated recipients has not been as frequent. Purpose Our aim was to evaluate and compare after transplantation, donor and recipient perceptions of donation. Methods After transplantation 35 recipients and 45 donors completed a sociodemographic and a donation perception questionnaire. We applied t...
Pancreas-Kidney Transplantation: Complications and Readmissions in 9-Years of ...
Martins, L.; Henriques, A.C.; Dias, L.; Almeida, M.; Pedroso, S.; Freitas, C.; Pereira, S.; Fructuoso, M.; Dores, J.; Oliveira, F.; Almeida, R.ABSTRACT Over years, we have performed 93 simultaneous pancreas-kidney transplants (SPKT) The morbidity of this procedure is high compared with kidney transplantation alone; readmissions are frequent and costs are higher. Herein we have presented the complica- tions during follow-up of these 93 patients. Their mean age was 34 years and prior dialysis time was 32 25 months. The median hospital stay on the first...
Bone Mineral Density After Simultaneous Kidney–Pancreas
Pereira, S.; Pedroso, S.; Martins, L.; Santos, P.; Almeida, M.; Freitas, C.; Dias, L.; Dores, J.; Almeida, R.; Henriques, A.C.; Teixeira, M.ABSTRACT Bone disease and an high risk of fractures are major problems in transplantation. Among diabetic patients undergoing simultaneous kidney–pancreas (SKP) transplantation, there are few studies assessing long-term effects on bone mass. The aim of this study was to evaluate bone mineral density (BMD) over 4 years follow-up after SKP transplantation. Fifty-seven patients had 22.8 5.3 years of prior diabete...
Pancreas-Kidney Transplantation and the Evolution of
Martins, L.; Malheiro, J.; Henriques, A.C.; Dias, L.; Dores, J.; Oliveira, F.; Seca, R.; Almeida, R.; Sarmento, A.M.; Cabrita, A.; Teixeira, M.ABSTRACT The recurrence or persistence of pancreatic autoantibodies after pancreas-kidney trans- plantation (PKT) is an intriguing finding. We prospectively analyzed 77 PKTs, searching for risk factors for the expression of these autoimmune markers and their impact on pancreas graft function. Among the 77 PKTs, 24.7% had HLA matches, 20.8% displayed delayed graft function, and 14.3% had acute rejection episode...
Impact Assessment in Living Kidney Donation: Psychosocial Aspects
Frade, I.C.; Fonseca, Isabel; Dias, L.; Henriques, A.C.; Martins, La Salete; Santos, J.; Sarmento, M.; Lopes, A.ABSTRACT Background. Living donor kidney transplantation has positive influence on graft survival and recipient quality of life (QoL)We assessed the psychosocial impact of donation to the donor. Methods. Before and after the procedure 32 living kidney donors (mean age 41 years) completed the Zung Self-Rating Anxiety and Depression Scales; Sociodemographic, Short-Form 36 Health Survey (SF-36)and Donation Percep...
Impact of hepatitis C virus on renal transplantation: association with poor sur...
Pedroso, S.; Martins, La Salete; Fonseca, Isabel; Dias, L.; Henriques, A.C.; Sarmento, A.M.; Cabrita, A.Transplant Proc. 2006 Jul-Aug;38(6):1890-4. Impact of hepatitis C virus on renal transplantation: association with poor survival. Pedroso S, Martins L, Fonseca I, Dias L, Henriques AC, Sarmento AM, Cabrita A. Nephrology and Transplant Departments, Hospital Geral de Santo António, Largo Professor Abel Salazar, 4050-011 Porto, Portugal. sofiapedroso@sapo.pt Abstract Data concerning the effect of hepatitis C virus...
Impact of Homocysteinemia on Long-Term Renal Transplant Survival
Fonseca, Isabel; Martins, La Salete; Queirós, J.; Mendonça, D.; Dias, L.; Sarmento, A.M.; Henriques, A.C.; Cabrita, A.Impact of Homocysteinemia on Long-Term Renal Transplant Survival I. Fonseca, L. Martins, J. Queirós, D. Mendonça, L. Dias, A.M. Sarmento, A.C. Henriques, and A. Cabrita ABSTRACT Aim. We prospectively followed cohort of 202 renal transplant recipients for years to examine the impact of fasting homocysteinemia on long-term patient and renal allograft survival. Methods. Cox proportional hazards regression analysi...
Homocysteine levels in pediatric renal transplant recipients.
Mota, C.; Fonseca, Isabel; Santos, M.J.; Costa, T.; Faria, M.S.; Henriques, A.C.; Sarmento, A.M.; Pereira, E.; Pereira, M.Transplant Proc. 2003 May;35(3):1093-5. Homocysteine levels in pediatric renal transplant recipients. Mota C, Fonseca I, Santos MJ, Costa T, Faria MS, Henriques AC, Sarmento AM, Pereira E, Pereira M. Department of Paediatric Nephrology, Maria Pia Children's Hospital, R. da Boavista, 827, 4050-111, Porto, Portugal. ccmotacosta@hotmail.com PMID: 12947872 [PubMed - indexed for MEDLINE