Background: The World Health Organization has identified Helicobacter pylori, a Gram-negative bacterium responsible for several gastric disorders, as one of the pathogenic bacteria that requires newer non-antibiotic approaches for its management. We previously demonstrated that nanostructured lipid carriers (NLC) loaded with docosahexaenoic acid (DHA-NLC)have excellent in vitro performance against H. pylori. Ma...
Coronaviruses (CoVs) are part of the Coronaviridae family, and the genera Gamma (γ) and Delta (δ) are found mostly in birds. Migratory birds have an enormous potential for dispersing pathogenic microorganisms. Ducks (order Anseriformes) can host CoVs from birds, with pathogenic expression and high economic impact. This study aimed to identify and characterize the diversity of CoVs in migratory ducks from Portug...
Acetalization of glycerol with pentanal was carried out in the presence of SBA-15 with sulfonic acid groups. Materials with different amounts of sulfonic acid groups were prepared. It was observed that the catalytic activity increases with the amount of sulfonic acid groups on SBA-15 until a maximum. With high amount of sulfonic groups, a decrease of activity is observed. All catalysts show high selectivity to ...
A infeção por estrongilídeos gastrointestinais tem-se revelado como um dos fatores com maior impacto económico na produção de ovinos. Esse impacto manifesta-se tanto de uma forma direta (tratamento, profilaxia, morte) como de forma indireta (atraso no crescimento, quebras na produção, maior suscetibilidade a outras doenças). O controlo parasitário com base no uso exclusivo de antihelmínticos não se tem revelado...
As infecções cervicais profundas constituem um verdadeiro desafio clínico, permanecendo na actualidade um problema relevante de saúde. Objectivo: Análise estatística dos internamentos com diagnóstico de celulite/abcesso cervical no Serviço de Otorrinolaringologia do Hospital Prof. Doutor Fernando Fonseca. Material e métodos: Avaliação de processos clínicos referentes a internamentos com o diagnóstico de entrada...
O mucocelo é uma lesão quística, benigna, expansiva dos seios perinasais. A sobreinfecção deste, designada de mucopiocelo, pode levar a um período de crescimento rápido, com maior risco de complicações. Relata-se o caso clínico de uma doente do sexo feminino, 59 anos, que recorreu ao Serviço de Urgência após crise inaugural de convulsão tónico-clónica generalizada, com queixas de aumento de volume periorbitário...
PURPOSE:Spontaneous parthenogenetically activated noninseminated oocytes and failed fertilized oocytes after ART activated by puromycin were studied to assess cleavage ability and the cytogenetic constitution of the resulting embryos. METHODS: Failed fertilized oocytes were exposed to puromycin, and whenever activation occurred, they were further cultured until arrest of development. FISH was used to assess the...
PURPOSE: Development of a hybridization technique for spermatozoa allowing the preservation of the head morphology. METHODS: FISH analysis of fixed semen samples from oligoasthenoteratozoospermia (OAT) patients with a normal somatic karyotype attending the Cytogenetics and the IVF Laboratories of a University hospital for semen analysis. In situ hybridization with centromeric probes for chromosomes X, Y, and 18...