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A survey of the European Reference Network EpiCARE on clinical practice for sel...

Baumgartner, Tobias; Carreño, Mar; Rocamora, Rodrigo; Bisulli, Francesca; Boni, Antonella; Brázdil, Milan; Horak, Ondrej; Craiu, Dana; Pereira, Cristina

Objective: Clinical care of rare and complex epilepsies is challenging, because evidence-based treatment guidelines are scarce, the experience of many physicians is limited, and interdisciplinary treatment of comorbidities is required. The pathomechanisms of rare epilepsies are, however, increasingly understood, which potentially fosters novel targeted therapies. The objectives of our survey were to obtain an o...


Long‐term efficacy and safety of eslicarbazepine acetate monotherapy for adults...

Trinka, Eugen; Rocamora, Rodrigo; Chaves, João; Moreira, Joana; Ikedo, Fábio; Soares‐da‐Silva, Patrício; Estol, Conrado; Newton, Mark; Carne, Ross

Objective: To assess the efficacy, safety, and tolerability of eslicarbazepine acetate (ESL) monotherapy during long-term treatment. Methods: An open-label extension (OLE) study was conducted in adults completing a phase 3, randomized, double-blind, noninferiority trial, during which they had received monotherapy with either once-daily ESL or twice-daily controlled-release carbamazepine (CBZ-CR) for newly diagn...


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