2 documents found, page 1 of 1
Generation of a library of carbohydrate-active enzymes for plant biomass decons...
Cardoso, Vânia; Bras, Joana L. A.; Costa, Ines F.; Ferreira, Luis M. A.; Gama, Luis; Vincentelli, Renaud; Henrissat, Bernard; Fontes, Carlos M.G.A.Áreas de pesquisa: Biochemistry & Molecular Biology ; Chemistry; In nature, the deconstruction of plant carbohydrates is carried out by carbohydrate-active enzymes (CAZymes). A high-throughput (HTP) strategy was used to isolate and clone 1476 genes obtained from a diverse library of recombinant CAZymes covering a variety of sequence-based families, enzyme classes, and source organisms. All genes were successful...
Comparative genomics of the major fungal agents of human and animal Sporotricho...
Teixeira, Marcus de Melo; Almeida, Luiz G. P. de; Barreira, Paula Kubitschek; Alves, Fernanda L.; Kioshima, Érika Seki; Abadio, Ana Karina RodriguesBackground: The fungal genus Sporothrix includes at least four human pathogenic species. One of these species, S. brasiliensis, is the causal agent of a major ongoing zoonotic outbreak of sporotrichosis in Brazil. Elsewhere, sapronoses are caused by S. schenckii and S. globosa. The major aims on this comparative genomic study are: 1) to explore the presence of virulence factors in S. schenckii and S. brasiliens...