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Analysis of shared heritability in common disorders of the brain

Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina

Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common varian...


Stimulation of MMP-1 and CCL2 by NAMPT in PDL cells

Nokhbehsaim, Marjan; Eick, Sigrun; Nogueira, Andressa Vilas Boas [UNESP]; Hoffmann, Per; Herms, Stefan; Fröhlich, Holger; Jepsen, Søren; Jäger, Andreas

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:44Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:43:33Z : No. of bitstreams: 1 2-s2.0-84884277332.pdf: 2996614 bytes, checksum: 24ac32304f7ee002eb509d1f7644b0c5 (MD5); Made available in DSpace on 2014-05-27T11:30:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-23; Periodontitis is an inflammatory d...

Date: 2014   |   Origin: Oasisbr

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