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Glycyrrhiza Genus: Enlightening Phytochemical Components for Pharmacological an...

Sharifi-Rad, J; Quispe, C; Herrera-Bravo, J; Belén, LH; Kaur, R; Kregiel, D; Uprety, Y; Beyatli, A; Yeskaliyeva, B; Kirkin, C; Özçelik, B; Sen, S

The Glycyrrhiza genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammat...


Cyperus spp.: A Review on Phytochemical Composition, Biological Activity, and H...

Taheri, Y; Herrera-Bravo, J; Huala, L; Salazar, LA; Sharifi-Rad, J; Akram, M; Shahzad, K; Melgar-Lalanne, G; Baghalpour, N; Tamimi, K

Cyperaceae are a plant family of grass-like monocots, comprising 5600 species with a cosmopolitan distribution in temperate and tropical regions. Phytochemically, Cyperus is one of the most promising health supplementing genera of the Cyperaceae family, housing ˜950 species, with Cyperus rotundus L. being the most reported species in pharmacological studies. The traditional uses of Cyperus spp. have been report...


Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literatu...

Islam, MT; Quispe, C; Herrera-Bravo, J; Sarkar, C; Sharma, R; Garg, N; Fredes, LI; Martorell, M; Alshehri, MM; Sharifi-Rad, J; Dastan, SD; Calina, D

Dengue remains one of the most serious and widespread mosquito-borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical envi...


Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Base...

Hossain, R; Quispe, C; Herrera-Bravo, J; Islam, MS; Sarkar, C; Islam, MT; Martorell, M; Martins, N; Al-Harrasi, A; Al-Rawahi, A; Sharifi-Rad, J

Lasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological data with their molecular mechanisms of action. A search was performed in databases such as PubMed, Science Direct, a...


Therapeutic Potential of Isoflavones with an Emphasis on Daidzein

Alshehri, MM; Sharifi-Rad, J; Herrera-Bravo, J; Jara, EL; Salazar, LA; Kregiel, D; Uprety, Y; Akram, M; Iqbal, M; Martorell, M; Torrens-Mas, M; Pons, DG

Daidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and estrogen receptor (ER) complex. Hence, daidzein puts forth shielding effects against a great number of diseases, especially those associated with the control of estr...


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