2 documents found, page 1 of 1
Endothelial activation is associated with albuminuria in multibacillary leprosy
Tessarolo, Louise Donadello; Meneses , Gdayllon Cavalcante; Bezerra, Gabriela Freire; Rocha, Thaiany Pereira da; Azevedo, Isabella Evelyn Prado deLeprosy may present kidney and endothelial abnormalities, being a risk factor for complications. However, the involvement of renal and vascular endothelia has been poorly investigated. We aimed to investigate if the levels of systemic endothelial biomarkers are associated with kidney abnormalities and the clinical forms of leprosy. This is a cross-sectional study with leprosy patients enrolled in January 2017 t...
Urinary monocyte chemotactic protein-1 (MCP-1) in leprosy patients : increased ...
Meneses, Gdayllon Cavalcante; Libório, Alexandre Braga; Daher, Elizabeth de Francesco; Silva Jr, Geraldo Bezerra da; Costa, Marcus Felipe Bezerra daBackground: We aimed to evaluate urinary MCP-1 and oxidative stress through urinary malondialdehyde (MDA) in leprosy and correlate them with traditional, but less sensitive markers of renal disease. Methods: This is a cross-sectional study of 44 patients with diagnosis of leprosy and no previous treatment. Skin smear was assessed through a bacteriological index - from 0 to 6+. Glomerular filtration rate (GFR), ...