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From the seaweeds`carrageenan composition to the hybrid carrageenans`hydrogel e...

Hilliou, Loic; Moraes, Izabel Cristina Freitas; Almeida, Pedro Lúcio; Marques de Almeida, Pedro

The carrageenan composition of 12 commercial seaweeds used in the production of hybrid carrageenans (HC) is estimated from the analysis of solid-state NMR spectra and is systematically compared with the chemical structure of HC extracted in hot water. 1H NMR showed that the isolated HC contain from 5 to 80 mol% kappacarrageenan, from 90 to 10 mol% iota-carrageenan, while from 8 to 23 mol% biological precursors ...


Tuning the drug multimodal release through a co-assembly strategy based on magn...

Veloso, Sérgio R. S.; Tiryaki, Ecem; Spuch, Carlos; Hilliou, Loic; Amorim, C. O.; Amaral, V. S.; Coutinho, Paulo J. G.; Ferreira, Paula M. T.

Self-assembled short peptide-based gels are highly promising drug delivery systems. However, implementing a stimulus often requires screening different structures to obtain gels with suitable properties, and drugs might not be well encapsulated and/or cause undesirable effects on the gel's properties. To overcome this challenge, a new design approach is presented to modulate the release of doxorubicin as a mode...


Polyhydroxyalkanoates from industrial cheese whey: production and characterizat...

Carvalheira, Mónica; Hilliou, Loic; Oliveira, Catarina S. S.; Guarda, Eliana C.; Reis, Maria A. M.

The composition of polyhydroxyalkanoate (PHA) monomers affects the properties and final applications of PHA polymers. This study focused on the feasibility of producing tailored PHA differing in hydroxyvalerate (HV) content, through manipulation of the acidogenic fermented stream composition, and on the characterization of PHA properties to determine the best composition for melt processing. Cheese whey was use...


Rheo-optical characterization of liquid crystalline acetoxypropylcellulose melt...

Teixeira, Paulo F.; Fernandes, Susete N.; Canejo, João; Godinho, Maria Helena; Covas, José A.; R. Leal, Catarina; Hilliou, Loic

The rheological and structural characteristics of acetoxypropylcellulose (APC) nematic melt are studied at shear rates ranging from 10 s(-1) to 1000 s(-1) which are relevant to extrusion based processes. APC shows a monotonic shear thinning behavior over the range of shear rates tested. The negative extrudate-swell shows a minimum when a critical shear rate (gamma) over dot(c) is reached. For shear rates smalle...


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