7 documents found, page 1 of 1
Experimental validation of time-explicit ultrasound propagation models with sou...
Fernandes, Nuno Alexandre Tavares Campos; Sharma, Shivam; Arieira, Ana Filipa Amorim; Hinckel, Betina; Silva, Filipe SamuelUltrasonic wave attenuation in biological tissues arises from complex interactions between mechanical, structural, and fluidic properties, making it essential to identify dominant mechanisms for accurate simulation and device design. This work introduces a novel integration of experimentally measured tissue parameters into time-explicit nonlinear acoustic wave simulations, in which the equations are directly so...
A Python FDTD method algorithm for 1D planar acoustic wave propagation: Simulat...
Fernandes, Nuno Alexandre Tavares Campos; Arieira, Ana Filipa Amorim; Hinckel, Betina; Silva, Filipe Samuel; Leal, Ana Isabel Neto CardosoNon-invasive techniques, such as high-frequency ultrasound, have emerged as promising therapeutic tools for neurological disorders, including Parkin-son’s disease and Alzheimer’s disease. By targeting specific brain regions, ultrasound stimulation modulates neural activity and induces beneficial physiological responses. However, simulating high-frequency acoustic wave propagation in biological tissues presents ...
Unlocking the secrets of knee joint unloading: a systematic review and biomecha...
Fernandes, Nuno Alexandre Tavares Campos; Arieira, Ana Filipa Amorim; Hinckel, Betina; Silva, Filipe Samuel; Carvalho, Óscar Samuel NovaisBackground/Objectives: This review analyzes the effects of invasive and non-invasive methods of knee joint unloading on knee loading, employing a biomechanical model to evaluate their impact. Methods: PubMed, Web of Science, Cochrane, and Scopus were searched up to 15 May 2024 to identify eligible clinical studies evaluating Joint Space Width, Cartilage Thickness, the Western Ontario and McMaster Universities O...
Micro and macromechanical modelling and simulation of bio elastomeric composite...
Fernandes, Nuno Alexandre Tavares Campos; Alves, Diana Isabel Sousa; Ferreira, Diana P.; Arieira, Ana Filipa Amorim; Silva, Filipe SamuelThis paper focuses on the virtual development of elastomeric composites incorporating natural fibers (Cordyline Australis) and an eco-friendly silicone matrix for medical phantoms that replicate the acoustic properties of human cranial skin. Micro- and macro-mechanical finite element models in COMSOL Multiphysics will be developed to simulate the anisotropic stress-strain behaviour of the composites under diffe...
Sustainable tunable anisotropic ultrasound medical phantoms for skin, skeletal ...
Fernandes, Nuno Alexandre Tavares Campos; Alves, Diana Isabel Sousa; Ferreira, Diana P.; Monteiro, Maria; Arieira, Ana; Silva, Filipe SamuelMedical phantoms are essential to imaging calibration, clinician training, and the validation of therapeutic procedures. However, most ultrasound phantoms prioritize acoustic realism while neglecting the viscoelastic and anisotropic properties of fibrous soft tissues. This gap limits their effectiveness in modeling realistic biomechanical behavior, especially in wave-based diagnostics and therapeutic ultrasound...
Optimization of red to near-infrared stimulation by light-emitting diodes to in...
Oliveira, Cátia Sofia Dias; Padrão, Jorge; Hinckel, Betina; Carvalho, Óscar Samuel Novais; Leal, AnaLearning objectives: Light-emitting diodes (LEDs) in near-infrared spectrum (810, 850 and 940 nm) enhanced cellular metabolism in a dose-dependent manner. Operation mode, power density, duration and periodicity must be considered in tailoring photobiomodulation (PBM) protocols for specific clinical scenarios. PBM by LEDs enhanced cells´ activity with minimal temperature increase, being a feasible and safe alter...
Mechanical stimulation of human chondrocytes by ultrasound as a bioinspired str...
Oliveira, Sofia; Padrão, Jorge; Catarino, Susana Oliveira; Monteiro, Francisca Machado; Zille, Andrea; Silva, Filipe Samuel; Hinckel, Betina[Excerpt] Articular cartilage is naturally subjected to mechanical forces during knee joint loading. A constant and physiological loading of articular cartilage is essential for chondrocytes, the resident cells, that sense the mechanical deformations, activating their intracellular mechanisms to regulate and maintain the tissue homeostasis. However, either excessive or low magnitude mechanical loading may distu...