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High levels of immunosuppression are related to unfavourable outcomes in hospit...

Marques, Claudia Diniz Lopes; Kakehasi, Adriana Maria; Pinheiro, Marcelo Medeiros; Mota, Licia Maria Henrique; Albuquerque, Cleandro Pires

Objectives To evaluate risk factors associated with unfavourable outcomes: emergency care, hospitalisation, admission to intensive care unit (ICU), mechanical ventilation and death in patients with immune-mediated rheumatic disease (IMRD) and COVID-19. Methods Analysis of the first 8 weeks of observational multicentre prospective cohort study (ReumaCoV Brasil register). Patients with IMRD and COVID-19 according...

Date: 2021   |   Origin: Oasisbr

Molecular and cellular biomarkers of COVID-19 prognosis : protocol for the pros...

Kurizky, Patricia Shu; Nóbrega, Otávio T.; Soares, Alexandre Anderson de Sousa Munhoz; Aires, Rodrigo Barbosa; Albuquerque, Cleandro Pires de

Background: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...

Date: 2021   |   Origin: Oasisbr

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