8 documents found, page 1 of 1
Desafios no seguimento dos pacientes submetidos à cirurgia por câncer de prósta...
Santos, Adriele Machado dos; Dornelas, Conceição Aparecida; Hirth, Carlos Gustavo; Farias, Henrique Carvalho LimaO câncer de próstata é a segunda neoplasia mais incidente em homens no Brasil. A evolução da doença é lenta mas a curva de mortalidade apresenta perfil ascendente. Estima-se que em 2016, 28,6% dos diagnósticos de neoplasia serão de próstata, enquanto no Ceará esse valor corresponde a 27,1%. Objetivou-se identificar os desafios no seguimento dos pacientes submetidos à prostatectomia radical no Hospital Universit...
FUS, PDSS2, SMAD4, CUL2 e HSPA9 no tecido prostático: como possíveis marcadores...
Hirth, Carlos GustavoProstatic adenocarcinoma is the second-most prevalent type of neoplasia in men, with a considerable divergence between the number of new cases and mortality. Thus, risk stratification is important when planning therapy. A range of markers have been proposed to predict disease development. Recent proteomic studies suggest proteins like FUS, PDSS2, DERL1, YBX1, pS6, SMAD4, CUL2 and HSPA9 may be useful in stratifi...
Tumor epitelial e estromal misto do rim: relato de caso
Barbosa, Francisco Flávio; Oliveira, Adriana Regina Vilarinho de; Sousa, Emília Tomé; Hirth, Carlos GustavoThe mixed epithelial and stromal tumor of the kidney is a rare neoplasm, characterized by its biphasic histopathological pattern, formed by epithelial and stromal elements. It predominates in females, in perimenopause and its pathogenesis is still unknown. We report the case of a 54-year-old female patient who started recurrent bouts of right flank pain and dysuria. The imaging exams revealed complex cystic les...
Evaluation of the diagnostic potential of CD1a immunohistochemistry for viscera...
Gadelha, Sami de Andrade Cordeiro; Cunha, Maria do Perpétuo Socorro Saldanha da; Coelho, Gabriela Maia; Marinho, Tamises Melo SiqueiraVisceral Leishmaniasis is a public health problem caused by protozoans of the genus Leishmania. K39 serological test is commonly used in the initial investigation, with high specificity, but variable sensitivity. Amastigotes can be identified by optical microscopy, however, the differential diagnosis with cellular debris or other intracellular parasites is necessary. Recent studies have raised the possibility o...
Transplante de tecido ovariano criopreservado e restauração do metabolismo ósse...
Silva, Lígia Helena Ferreira Melo e; Silva, João Marcos de Meneses e; Salama, Mahmoud; Pinheiro, Luiz Gonzaga Porto; Lunardi, Franciele OsmariniObjectives: to evaluate estradiol levels and autotransplantation heated ovarian tissue effects, after vitrification, on rats bone metabolism previously oophorectomized bilaterally. Methods: experimental study with 27 rats aged 11 to 12 weeks and weighing 200g to 300g, submitted to bilateral oophorectomy and ovarian tissue cryopreservation for subsequent reimplantation. Animals were divided into two groups, A an...
PanCD44 immunohistochemical evaluation in Prostatectomies from patients with ad...
Hirth, Carlos Gustavo; Santos, Adriele Machado dos; Cerqueira, João Batista Gadelha de; Jamacaru, Francisco Vagnaldo FechineIntroduction. CD44 has been proposed as a prognostic marker and a stem cell marker but studies in patients with prostate cancer have yielded inconsistent results. Patients and Methods. Patients submitted to radical prostatectomy between 2008 and 2013 at a university hospital were followed with biannual serum PSA tests to determine the biochemical recurrence (BR). Archived paraffin blocks with neoplastic and non...
Splenogonadal fusion associated with delayed skeletal maturation : a case repor...
Medeiros Neto, José Urbano de; Hirth, Carlos Gustavo; Dornelas, Conceição Aparecida; Cerqueira, João Batista Gadelha de; Fujiike, Dennis TomioIn this report of a 13-year old boy, we describe the first case of splenogonadal fusion (SGF) associated with growth hormone deficiency, delayed skeletal maturation and stunting, and provide a review of the literature on SGF based on a search in major medical indexes using the descriptors “splenogonadal”, “splenogonadal fusion” and “congenital anomalies of the spleen”. Predominant in males (15:1), SGF is a rare...
Valor prognóstico de marcadores de diferenciação neuroendócrina e de células-tr...
Hirth, Carlos GustavoThis study aimed to evaluate the new immunohistochemical markers related to neuroendocrine differentiation induction and stem cells with prognostic factors and biochemical recurrence in patients submitted to radical prostatectomy. Therefore, patients operated at the Hospital Walter Cantídio, Federal University of Ceará, in the period of 2008-2013, underwent clinical and outpatient follow-up, between the years 2...