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Full physicochemical and biocompatibility characterization of a supercritical C...

Souto-Lopes, M; Grenho, L; Manrique, YA; Dias, MM; Fernandes, MH; Monteiro, FJ; Salgado, C

Despite bone's innate self-renewal capability, some periodontal pathologic and traumatic defects' size inhibits full spontaneous regeneration. This current research characterized a 3D porous biodegradable nano-hydroxyapatite/chitosan (nHAp/CS, 70/30) scaffold for periodontal bone regeneration, which preparation method includes the final solvent extraction and sterilization through supercritical CO2 (scCO2). Mic...


Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara

Salgado, C; Garcia, AM; Rúbio, C; Cunha, F

A mononucleose infeciosa é uma das principais manifestações clínicas da infeção pelo vírus Epstein-Barr. Nesta síndrome, a elevação das aminotransferases é comum mas a colestase é rara, havendo poucos casos descritos na literatura. Adolescente, 14 anos, sexo feminino, admitida no serviço de urgência por febre, odinofagia e adenomegália cervical. Iniciou tratamento com amoxicilina e dois dias depois iniciou icte...


Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara

Salgado, C; Garcia, AM; Rúbio, C; Cunha, F

Infectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and tw...


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