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High-Throughput Drug Screening Revealed That Ciclopirox Olamine Can Engender Ga...

Pádua, Diana; Figueira, Paula; Pinto, Mariana; Maia, André Filipe; Peixoto, Joana; Lima, Raquel T; Pombinho, António; Pereira, Carlos Filipe

Cancer stem cells (CSCs) are relevant therapeutic targets for cancer treatment. Still, the molecular circuits behind CSC characteristics are not fully understood. The low number of CSCs can sometimes be an obstacle to carrying out assays that explore their properties. Thus, increasing CSC numbers via small molecule-mediated cellular reprogramming appears to be a valid alternative tool. Using the SORE6-GFP repor...

Date: 2023   |   Origin: Estudo Geral - Universidade de Coimbra
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