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Antifungal activity of liriodenine on clinical strains of Cryptococcus neoforma...

Levorato-Vinche,Adriele Dandara; Melhem,Marcia de Souza Carvalho; Bonfietti,Lucas Xavier; de-la-Cruz-Chacón,Iván; Boaro,Carmen Sílvia Fernandes

Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC dai...

Date: 2022   |   Origin: Oasisbr
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