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Global Prevalence of Young-Onset Dementia: A Systematic Review and Meta-analysis

Hendriks, S; Peetoom, K; Bakker, C; van der Flier, WM; Papma, JM; Koopmans, R; Verhey, FRJ; de Vugt, M; Köhler, S; Withall, A; Parlevliet, JL

Importance: Reliable prevalence estimates are lacking for young-onset dementia (YOD), in which symptoms of dementia start before the age of 65 years. Such estimates are needed for policy makers to organize appropriate health care. Objective: To determine the global prevalence of YOD. Data sources: The PubMed, Embase, CINAHL, and PsycInfo databases were systematically searched for population-based studies on the...


Maternal complications in pregnancy and wheezing in early childhood: A pooled a...

Zugna, D; Galassi, C; Annesi-Maesano, I; Baïz, N; Barros, H; Basterrechea, M; Correia, S; Duijts, L; Esplugues, A; Fantini, MP; Forastiere, F; Gascon, M

Background: Evidence on the effect of maternal complications in pregnancy on wheezing in offspring is still insufficient. Methods: A pooled analysis was performed on individual participant data from fourteen European birth cohorts to assess the relationship between several maternal pregnancy complications and wheezing symptoms in the offspring. Exposures of interest included hypertension and preeclampsia, diabe...


European birth cohorts for environmental health research

Vrijheid, M; Casas, M; Bergström, A; Carmichael, A; Cordier, S; Eggesbø, M; Eller, E; Fantini, MP; Fernández, MF; Fernández-Somoano, A; Gehring, U

Background: Many pregnancy and birth cohort studies investigate the health effects of early-life environmental contaminant exposure. An overview of existing studies and their data is needed to improve collaboration, harmonization, and future project planning. Objectives: Our goal was to create a comprehensive overview of European birth cohorts with environmental exposure data. Methods: Birth cohort studies were...


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